Hershel Raff, PhD, FAAAS, FAPS
Professor, Medicine, Physiology and Surgery; Director, Endocrine Research Laboratory
- Aurora St. Luke's Medical Center
2801 W. KK River Pkwy., Suite 260
Milwaukee, WI 53215
University of California-San Francisco, Postdoctoral Fellowship in Endocrinology
Adrenal, Stress, Cushing’s syndrome, Adrenal Insufficiency
- Physiology and Surgery in the MCW School of Medicine
- MCW School of Pharmacy
- Biomedical Sciences, Marquette University
Hershel Raff is Professor of Medicine in the Division of Endocrinology and Molecular Medicine and also a Professor in the MCW Pharmacy School. He holds secondary appointments in the Departments of Physiology and Surgery. He is the Director of the Endocrine Research Laboratory at Aurora St. Luke's Medical Center of the Aurora Research Institute. He received a BA in Music from Union College in Schenectady, NY. He earned his PhD in Environmental Physiology from the Johns Hopkins University Bloomberg School of Public Health. He was a post-doctoral fellow in Endocrinology at the University of California, San Francisco (UCSF). Dr. Raff came to MCW in 1983 as an Assistant Professor and rose to the rank of Professor in 1991. He is also an Adjunct Professor in Biomedical Sciences at Marquette University.
- Associate Editor of Endocrinology
- UpToDate Author/Editor for Clinical Laboratory Testing – Hypothalamic-Pituitary Adrenal Function
- Editorial Board, Journal of the Endocrine Society
- Faculty Opinions (Faculty of 1000), Physiology, Head of the Endocrinology Section
- Advancing a Healthier Wisconsin Endowment (AHW) Merit Reviewer
- 2022 We Care Fund Scientific Review Committee, Department of Surgery, Medical College of Wisconsin, Reviewer
- Course Director, Medical Student Endocrinology/Reproduction Unit
- Course Director, Introduction to Organ Systems Physiology for Graduate Students
- Faculty Advisor, Medical Student Assembly
- Clinical and Translation Science Institute of Southeast Wisconsin (CTSI), CTSI
- Scientific Review Oversight Committee
- Medical School Nominating Committee
- Medical School Curriculum and Evaluation Committee (CEC)
- Graduate Studies Council Course Evaluation Committee
- Graduate Studies Council - Rank Committee
Advocate Aurora Health/Aurora St. Luke's Medical Center Internal
- Advocate Aurora Health, Advocate Aurora Research Institute, Intramural Scientific Review Committee
- Chairman, Institutional Animal Care and Use Committee (IACUC)
- Radiation Safety Committee
Dr. Raff’s basic research focuses on the hypothalamic-pituitary-adrenal axis and the short-and long-term consequences of neonatal stress and therapeutics. His translational research focuses on the interaction of obesity and pain in human adolescents. His clinical research focuses on the development of diagnostic endocrine tests and, in particular, using the measurement of salivary cortisol to evaluate the hypothalamic-pituitary-adrenal axis in a variety of human diseases and stress models and the development of cortisol assays to use in ACTH stimulation testing.
Dr. Raff is heavily involved in medical, graduate, pharmacy and undergraduate education. He is Course Director Endocrinology/Reproduction Integrated Course for medical students in their preclinical phase. He teaches first year endocrine physiology to medical and pharmacy students and Endocrine Clinical Fellows. He is the course director of the Introduction to Organ Systems Physiology for first year graduate students. Dr. Raff is the author of two textbooks: Vander’s Human Physiology, an undergraduate textbook, and Medical Physiology: A Systems Approach, a medical student-level textbook. He also teaches Applied and Rehabilitative Systems Physiology at Marquette University College of Health Science. He was an inaugural inductee into the MCW Society of Teaching Scholars in 1991 and was elected to Alpha Omega Alpha as a Faculty Member by the MCW senior medical student class of 2005.
- Evaluating the interaction of neonatal stress and common clinical interventions on the hypothalamic-pituitary-adrenal (HPA) axis and metabolism in an animal model of human prematurity.
- Studying the role of the HPA axis in relapse of opioid addiction in a rat model of sleep disruption.
- Using a newly developed liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to measure salivary cortisol and cortisone in the diagnosis of Cushing’s syndrome.
- Evaluation of the ACTH (cosyntropin) stimulation test for the diagnosis of adrenal insufficiency utilizing new generation cortisol assays.
- Measuring serum and salivary biomarkers in patients with mild traumatic brain injury and obesity.
(Raff H.) Pituitary. 2022 Oct;25(5):698-700 PMID: 35334030 SCOPUS ID: 2-s2.0-85127277574 03/26/2022
(Gonzalez PA, Simcox J, Raff H, Wade G, Von Bank H, Weisman S, Hainsworth K.) Lipids Health Dis. 2022 Aug 30;21(1):80 PMID: 36042489 PMCID: PMC9426222 SCOPUS ID: 2-s2.0-85136987097 08/31/2022
(Medda R, Raff H, Shaker J, Guda N.) Am J Gastroenterol. 2022 May 01;117(5):813-814 PMID: 35080511 SCOPUS ID: 2-s2.0-85129996587 01/27/2022
(Gadelha MR, Karavitaki N, Fudin J, Bettinger JJ, Raff H, Ben-Shlomo A.) Pituitary. 2022 Feb;25(1):52-63 PMID: 35066756 SCOPUS ID: 2-s2.0-85123498706 01/24/2022
(Raff H, Phillips J, Simpson P, Weisman SJ, Hainsworth KR.) Stress. 2022 Jan;25(1):331-336 PMID: 36330600 SCOPUS ID: 2-s2.0-85141327101 11/05/2022
(Gehrand AL, Phillips J, Welhouse KD, Siddiqui H, Schulgit M, Hoffman J, Hunt H, Raff H.) Endocrinology. 2022 Jan 01;163(1) PMID: 34791109 SCOPUS ID: 2-s2.0-85122710601 11/19/2021
(Fleseriu M, Auchus R, Bancos I, Ben-Shlomo A, Bertherat J, Biermasz NR, Boguszewski CL, Bronstein MD, Buchfelder M, Carmichael JD, Casanueva FF, Castinetti F, Chanson P, Findling J, Gadelha M, Geer EB, Giustina A, Grossman A, Gurnell M, Ho K, Ioachimescu AG, Kaiser UB, Karavitaki N, Katznelson L, Kelly DF, Lacroix A, McCormack A, Melmed S, Molitch M, Mortini P, Newell-Price J, Nieman L, Pereira AM, Petersenn S, Pivonello R, Raff H, Reincke M, Salvatori R, Scaroni C, Shimon I, Stratakis CA, Swearingen B, Tabarin A, Takahashi Y, Theodoropoulou M, Tsagarakis S, Valassi E, Varlamov EV, Vila G, Wass J, Webb SM, Zatelli MC, Biller BMK.) Lancet Diabetes Endocrinol. 2021 Dec;9(12):847-875 PMID: 34687601 PMCID: PMC8743006 SCOPUS ID: 2-s2.0-85122111053 10/24/2021
(Javorsky BR, Raff H, Carroll TB, Algeciras-Schimnich A, Jit Singh R, Colón-Franco JM, Findling JW.) J Endocr Soc. 2021 Sep 01;5(9):bvab113 PMID: 34278181 PMCID: PMC8279072 SCOPUS ID: 2-s2.0-85112025664 07/20/2021
(Javorsky BR, Raff H, Carroll TB, Algeciras-Schimnich A, Singh RJ, Colón-Franco JM, Findling JW.) J Endocr Soc. 2021 Apr 01;5(4):bvab022 PMID: 33768189 PMCID: PMC7975762 03/27/2021
(Hainsworth KR, Simpson PM, Raff H, Grayson MH, Zhang L, Weisman SJ.) Pain Rep. 2021;6(1):e916 PMID: 33977184 PMCID: PMC8104468 05/13/2021
(Rolon S, Huynh C, Guenther M, Gardezi M, Phillips J, Gehrand AL, Raff H.) Physiol Rep. 2021 Jan;9(1):e14663 PMID: 33393733 PMCID: PMC7780235 SCOPUS ID: 2-s2.0-85099269848 01/05/2021
(Kannankeril J, Carroll T, Findling JW, Javorsky B, Gunsolus IL, Phillips J, Raff H.) J Endocr Soc. 2020 Oct 01;4(10):bvaa107 PMID: 32935666 PMCID: PMC7480956 09/17/2020