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Postdoctoral Research Opportunities

Transcriptional Regulation of GI Development, Function, and Disease

A postdoctoral research position is available in the Battle laboratory for a highly motivated candidate interested in leading innovative research directed at understanding mechanisms of transcriptional regulation of gastrointestinal development, function, and disease. Projects in the lab focus on how transcription factors establish boundaries in the GI tract, how transcription factors regulate early aspects of GI development, and how these mechanisms relate to diseases such as short bowel syndrome, inflammatory bowel disease, Barrett’s esophagus, esophageal adenocarcinoma, and gastric cancer. Our team uses genetically modified mouse lines and pluripotent stem cell/primary tissue derived cell models grown as 2D, 3D, and air-liquid interface cultures. We assess molecular and cellular phenotypes using innovative next-generation sequencing approaches (e.g., RNA-Seq, single cell RNA-Seq, ChIP-Seq, CUT&TAG), qRT-PCR, immunoblot, histology, immunohistochemistry, and immunofluorescent protein staining. The successful applicant will bring their experience in cell, developmental, and/or molecular biology to complement our existing research program and to develop new research directions. Experience with approaches described would be beneficial. Experience with animal handling is also desired. Outstanding communication and interpersonal skills are essential. Opportunities are available to participate in national and international scientific conferences and to apply for independent funding.

Candidates should have a PhD in Cell and Molecular Biology, Developmental Biology, or a related field. Interested individuals should submit a CV, description of research ideas, interests, and career goals, and the names of three references to Dr. Michele A. Battle at mbattle@mcw.edu.

View the Battle Laboratory website