Renal pathology deals with the diagnosis and characterization of non-tumor diseases of the kidneys. Renal pathologists work closely with nephrologists, transplant surgeons and urologists, who typically obtain diagnostic specimens via percutaneous renal biopsy and nephrectomy. In non-tumor kidney disease tissue, the renal pathologist must synthesize findings from light microscopy, electron microscopy, and immunofluorescence with clinical information to obtain a definitive diagnosis.