News in Biophysics
Biophysics News is a quarterly MCW departmental newsletter aimed at enhancing departmental engagement through information and good news sharing.
Biophysics Researchers Publish Study on Modified Polyphenols for Use in Cancer and Immune Therapies
Gang Cheng, PhD, Balaraman Kalyanaraman, PhD, and international collaborating authors, published an article in Cancers, which discusses the selective modification of several plant-based compounds that inhibit tumor growth in order to increase their potency.
Biophysics Graduate Student Patrick Brennan Receives F31 Grant
Patrick Brennan, a Biophysics graduate student in the Lerch Lab, was awarded a two-year, $93,504 F31 grant from the National Heart, Lung, and Blood Institute.
Sam Bobholz, Fifth-Year PhD Student in Biophysics, Wins Paper of the Season Award
Sam Bobholz, a fifth-year PhD student in the Department of Biophysics, won the fall Paper of the Season Award from the Graduate School for his paper, Radio-Pathomic Maps of Cell Density Identify Brain Tumor Invasion beyond Traditional MRI-Defined Margins.
MCW Mourns the Passing of Dr. James S. Hyde
James S. Hyde, PhD, professor emeritus of biophysics, a pioneer in functional magnetic resonance imaging (fMRI) and one of the world’s leading authorities on brain connectivity and electron paramagnetic resonance (EPR) instrumentation, died on Saturday, Aug. 13, following a brief illness.
Christine Zeller Named Department Administrator for Biophysics
Christine Zeller has been named Department Administrator for Biophysics effective Aug. 15.
MCW Researchers Awarded US Patent for fMRI Surface Coil that Produces Faster, Higher-quality Images
Biophysics faculty are inventors of MCW’s recently issued US Patent for Strongly Coupled Fourth-Order Resonance Coil Systems for Enhanced Signal Detection, which pertains to a novel receive-only surface coil for functional magnetic resonance imaging (fMRI) with a significantly higher sensitivity compared with a standard fMRI coil of similar size.
Biophysics Researcher Coauthors Consensus Statement on Measurement of Reactive Oxygen Species
Balaraman Kalyanaraman, PhD, chair and professor of biophysics and the Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research, coauthored a consensus statement from an international group of researchers, which was published in Nature Metabolism.
Targeting Tumor and Tumor Microenvironment Vulnerabilities
Drs. Balaraman Kalyanaraman and Gang Cheng from MCW and Dr. Micael Hardy in France have published a review article that posits that mitochondria-targeted drugs combined with standard-of-care chemotherapy, radiation therapy, and immunotherapy are likely to have potentiating effects in cancer treatment.
Dr. Francesca Marassi Named Chair of Biophysics
MCW is pleased to announce the appointment of Francesca Marassi, PhD, as Chair of the Department of Biophysics at the Medical College of Wisconsin (MCW), effective October 1, 2022.
MCW Researcher Awarded US Patent for Mito-Lonidamine Compositions and Methods to Treat Cancer
Dr. Balaraman Kalyanaraman and collaborators at Aix-Marseille Université, France are inventors on MCW’s recently awarded US Patent for Mito-Lonidamine, Compositions and Methods of Use, which pertains to mitochondria-targeting cationic drugs and methods of using them to inhibit lung cancer proliferation and progression and metastasis to the brain.
Combinatorial Mitochondria-Targeted Drug Therapy as a Novel Option for Lung Cancer Prevention
Balaraman Kalyanaraman, PhD, chair and professor of biophysics and the Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research, collaborates with researchers from the Houston Methodist Research Institute and Aix-Marseille Université.
Melissa Prah Receives Outstanding Presentation Award
Melissa Prah, engineer II in the Schmainda lab in the Department of Biophysics, receives the American Society of Neuroradiology’s 2022 (ASNR22) Outstanding Presentation Award.
Microhelix Paves Way for Low-Cost Benchtop X-band Pulse EPR Spectrometers
Dr. Jason Sidabras and collaborators have published a paper that explores the use of a self-resonant microhelix to obtain DEER data using three orders of magnitude less power than commercially available resonators.
Innovative Therapy that "Tricks" and Destroys Cancer Cells Advances to Clinical Trial
Results from pre-clinical research show iron-like compound holds promise for treating patients with glioblastoma, an aggressive brain cancer
PEGylated Mitochondria-Targeted Drugs Have Potential in Cancer Treatment
Balaraman Kalyanaraman, PhD, and Gang Cheng, PhD, collaborate with researchers from Aix-Marseille Université and Houston Methodist Research Institute.
MCW Researchers Awarded US Patent for Mito-Metformin Compounds and Methods to Treat Cancer
Balaraman Kalyanaraman, PhD, and Jacek Zielonka, PhD, DSc, are two of the inventors on MCW’s recently awarded US Patent for Modified Mito-Metformin Compounds and Methods of Synthesis and Use Thereof.
Study Looks at Use of Mitochondria-Targeted Malaria Drug to Prevent Tumor Growth and Dissemination
Balaraman Kalyanaraman, PhD, chair and professor of biophysics and the Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research, collaborates with researchers at the Medical College of Wisconsin, Houston Methodist Research Institute, and Aix-Marseille Université.
Dr. Kathleen Schmainda Receives Perfect Score on NCI MPI R01 to Establish a Consensus DSC-MRI Protocol
Kathleen M. Schmainda, PhD, professor of biophysics, collaborates with researchers from MCW, Brown University, Barrow Neurological Institute, and Mayo Clinic.
Article by Biophysics Researcher Discusses Racial and Biological Disparities in Cancer Research
Balaraman Kalyanaraman, PhD, chair and professor of biophysics and the Harry R. & Angeline E. Quadracci Professor in Parkinson’s Research, discusses the use of mitochondria-targeted drugs to target vulnerabilities in tumor cells and in the tumor immune microenvironment to better understand biological disparity.
MCW, French Researchers are Inventors of US Patent for Mito-Magnolol Compounds to Treat Melanoma
Collaborators in the Department of Biophysics, along with collaborators at Aix-Marseille Université, France, are inventors on MCW’s recently awarded US Patent 11,083,739 for Mito-Magnolol Compounds and Methods of Synthesis and Use Thereof.
Medical College of Wisconsin
8701 Watertown Plank Rd.
Milwaukee, WI 53226
Directions to Biophysics (PDF)