Comprehensive Epilepsy Center
The MCW Comprehensive Epilepsy Program provides cutting-edge diagnostic and therapeutic options to patients with epilepsy in all age-groups. A programmatic approach is taken to pursue the goal of seizure freedom without adverse side effects.
Since 1991 Medical College of Wisconsin Comprehensive Epilepsy Program has specialized in helping people with difficult-to-control epilepsy. Patients from throughout Wisconsin and the upper Midwest receive care through the program – one of the first epilepsy programs in the state. Our goal is to improve patients’ quality of life by controlling their seizures with minimal side effects from medication.
The MCW Comprehensive Epilepsy Program takes a multidisciplinary approach to providing care to epilepsy patients in close collaboration with the their primary neurologists and other health care providers. The Departments of Neurology, Neurosurgery, and Neuroradiology, with the research benefits derived from the MCW Clinical Research Center and Biophysics Department, carefully tailor treatment to the specific needs of individual patients. Diagnostic options available to patients include Video-EEG monitoring, Ambulatory-EEG, Invasive Intracranial EEG studies, High resolution MR imaging with dedicated epilepsy protocols, Intracarotid Amobarbital Procedures (Wada test), fMRI, SPECT, PET, Magnetoencephalography (MEG), and direct electrical stimulation mapping of the cortex. All currently accepted therapies for epilepsy are available through our program including all anticonvulsants, drugs that are in clinical trials, all types of epilepsy surgery, Vagus Nerve Stimulation, as well as the ketogenic or modified Atkins diets. Our adult program also has extensive experience in catering to the special needs of women with epilepsy, especially those in the childbearing years.
Adult and pediatric components of the program are located in adjacent hospital complexes with separate epilepsy monitoring units and busy well established epilepsy surgery programs. The Adult Epilepsy Center based at Froedtert Hospital is also one of a few epilepsy centers in the United States to be certified by the Joint Commission International (formerly JCAHO). The Pediatric Epilepsy Center is housed at the Childrens’ Hospital of Wisconsin. The clinical program is a tertiary referral center for a large region of eastern Wisconsin and northern Illinois.
Drs. Christopher Inglese, Nadir Khan, Priya Monrad and Michael Schwabe provide care for children through the Pediatric Epilepsy Center.
Drs. Christopher Anderson, Humberto Battistini, Chad Carlson and Manoj Raghavan provide patient care at the Adult Epilepsy Center.
Neurosurgical procedures for our epilepsy program are performed by Drs. Wade M. Mueller and Sean Lew. Our neurosurgeons have partnered with our epilepsy specialists in conducting over 300 epilepsy surgeries, of all types, over the last 10 years alone. Our programs have extensive experience with Vagus Nerve Stimulation therapy for the control of seizures with more than 600 implantation procedures over the years.
The Neuropsychology program at MCW provides evaluations that are critical to the selection of patients for the surgical treatment of their epilepsy. Comprehensive neuropsychological testing includes assessment of memory, language, visual spatial skills, executive functioning and motor abilities as a means for lateralizing the origin of seizures and predicting cognitive outcome after surgical interventions. Providers in the Neuropsychology clinic who focus on epilepsy include Drs. Sara Swanson, David Sabsevitz, Jennifer Geiger, Jennifer Koop, and Kristin Smith.
The clinical fMRI program at MCW is an invaluable asset to the epilepsy surgery program for mapping vital areas of brain function prior to brain surgery, and for predicting language and memory outcome after temporal lobe surgeries. Magnetoencephalography (MEG) which is a new addition to our arsenal of diagnostic tools, not only provides a complimentary methodology to fMRI for function localization, but also allows localization of epileptic circuitry on patient-specific brain models.
The program hosts a monthly support group for patients with epilepsy and their families to provide educational opportunities as well as interactive sessions with various specialists on topics relating to epilepsy.
Our Epilepsy Program has greatly benefitted from a strong tradition of translational neuroimaging research which is a particular strength at the Medical College of Wisconsin. Research pioneered at our institution has been central to the development of clinical fMRI for the presurgical evaluation of patients with epilepsy and brain tumors. Other resources available for basic and applied research include a recently established state-of-the-art magnetoencephalography (MEG) laboratory, access to invasive EEG data, SISCOM, FDG-PET, Diffusion Tensor Imaging (DTI) with tractography, a Transcranial Magnetic Stimulation laboratory with real-time navigation capability and simultaneous EEG recording options, and a variety of tools for multimodal image registration.
More information about our Adult and Pediatric program:
Comprehensive Neuroscience Center
This new ten-bed Pediatric Epilepsy Monitoring Unit is located in Children’s Hospital of Wisconsin and contains state-of-the-art, video-EEG equipment. The Pediatric Epilepsy Monitoring Unit operates 24 hours a-day, seven days a week. The unit is staffed by a team of dedicated physicians, nurses and EEG technicians specializing in pediatric epilepsy. An on-site EEG lab and advanced techniques such as functional MRI (fMRI) enable noninvasive mapping of language and motor function as well as specialized diagnosis and monitoring. State-of-the-art software and analysis allows co-registration of data from multiple tests, enabling our epileptologists and neurosurgeon to better localize the seizure focus within the brain.
Level 4 Epilepsy Centers
The Adult and Pediatric Epilepsy Centers that constitute the MCW Comprehensive Epilepsy Program are both independently designated Level 4 epilepsy centers – the highest rating – by the National Association of Epilepsy Centers. A level 4 epilepsy center serves as a regional or national referral facility and offers:
- A complete evaluation for epilepsy
- Advanced neurodiagnostic techniques, including intracranial EEG studies
- Comprehensive medical, neuropsychological and psychosocial treatment
- Comprehensive treatments and surgical procedures for epilepsy
Joint Commission International
The Adult Comprehensive Epilepsy Center at Froedtert Hospital is certified by Joint Commission International as a Center of Excellence for Epilepsy since 2010. We are proud to be one of only four (4) hospitals in the United States that currently hold JCI certification for epilepsy.
Language Imaging Laboratory
The Language Imaging Laboratory at the Medical College of Wisconsin, led by Dr. Jeffrey Binder, has pioneered methods for presurgical functional localization of language and episodic memory systems through several NIH funded research programs. The center currently leads a NIH funded multicenter trial evaluating the value of fMRI for mapping language networks in patients undergoing dominant temporal lobe surgery.