Publications 

Recent Publications

• Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution.

  (Patel DD, Marsic D, Periasamy R, Zolotukhin S, Lipinski DM.) Transl Vis Sci Technol. 2022 08 01;11(8):28 PMID: 36018583 PMCID: PMC9428359 08/27/2022

• rAAV-mediated over-expression of acid ceramidase prevents retinopathy in a mouse model of Farber lipogranulomatosis.

  (Zhang H, Nagree MS, Liu H, Pan X, Medin JA, Lipinski DM.) Gene Ther. 2022 Jul 28 PMID: 35902747 07/29/2022

• Artificial intelligence-based strategies to identify patient populations and advance analysis in age-related macular degeneration clinical trials.

  (Yaghy A, Lee AY, Keane PA, Keenan TDL, Mendonca LSM, Lee CS, Cairns AM, Carroll J, Chen H, Clark J, Cukras CA, de Sisternes L, Domalpally A, Durbin MK, Goetz KE, Grassmann F, Haines JL, Honda N, Hu ZJ, Mody C, Orozco LD, Owsley C, Poor S, Reisman C, Ribeiro R, Sadda SR, Sivaprasad S, Staurenghi G, Ting DS, Tumminia SJ, Zalunardo L, Waheed NK.) Exp Eye Res. 2022 Jul;220:109092 PMID: 35525297 PMCID: PMC9405680 SCOPUS ID: 2-s2.0-85130394017 05/08/2022

• Pupillary Dilation in Research: More than Meets the Eye.

  (Szpernal J, Bachman Groth JA, Wynne N, Williams V, Spellecy R, Thuruthumaly C, Carroll J.) Curr Eye Res. 2022 Jul;47(7):965-977 PMID: 35499263 PMCID: PMC9276640 SCOPUS ID: 2-s2.0-85132654884 05/03/2022

• Axial Length Distributions in Patients With Genetically Confirmed Inherited Retinal Diseases.

  (Williams KM, Georgiou M, Kalitzeos A, Chow I, Hysi PG, Robson AG, Lingham G, Chen FK, Mackey DA, Webster AR, Hammond CJ, Prokhoda P, Carroll J, Michaelides M, Mahroo OA.) Invest Ophthalmol Vis Sci. 2022 06 01;63(6):15 PMID: 35704304 PMCID: PMC9206393 SCOPUS ID: 2-s2.0-85132131802 06/16/2022

• Comparison of Cone Mosaic Metrics From Images Acquired With the SPECTRALIS High Magnification Module and Adaptive Optics Scanning Light Ophthalmoscopy.

  (Wynne N, Heitkotter H, Woertz EN, Cooper RF, Carroll J.) Transl Vis Sci Technol. 2022 05 02;11(5):19 PMID: 35583887 PMCID: PMC9123519 SCOPUS ID: 2-s2.0-85130766763 05/19/2022

• Long-term retinal imaging of a case of suspected congenital rubella infection.

  (Langlo CS, Trotter A, Reddi HV, Schilter KF, Tyler RC, Udani R, Neitz M, Carroll J, Connor TB.) Am J Ophthalmol Case Rep. 2022 Mar;25:101241 PMID: 34977425 PMCID: PMC8688893 01/04/2022

• The Impact of Axial Eye Growth on Foveal Avascular Zone Measurements in Children.

  (Linderman RE, Heffernan E, Ferrante S, Bachman Groth J, Carroll J.) Optom Vis Sci. 2022 02 01;99(2):127-136 PMID: 34897231 PMCID: PMC8816819 SCOPUS ID: 2-s2.0-85124172597 12/14/2021

• Long-term retinal imaging of a case of suspected congenital rubella infection

  (Langlo CS, Trotter A, Reddi HV, Schilter KF, Tyler RC, Udani R, Neitz M, Carroll J, Connor TB.) American Journal of Ophthalmology Case Reports. March 2022;25 SCOPUS ID: 2-s2.0-85121217327 03/01/2022

• Ablation of mpeg+ Macrophages Exacerbates mfrp-Related Hyperopia.

  (Brandt ZJ, Collery RF, Besharse JC, Link BA.) Invest Ophthalmol Vis Sci. 2021 12 01;62(15):13 PMID: 34913948 PMCID: PMC8684298 SCOPUS ID: 2-s2.0-85122380090 12/17/2021

• Challenges Associated With Ellipsoid Zone Intensity Measurements Using Optical Coherence Tomography.

  (Lee KE, Heitkotter H, Carroll J.) Transl Vis Sci Technol. 2021 10 04;10(12):27 PMID: 34665233 PMCID: PMC8543396 SCOPUS ID: 2-s2.0-85119458060 10/20/2021

• Theoretical versus empirical measures of retinal magnification for scaling AOSLO images.

  (Heitkotter H, Salmon AE, Linderman RE, Porter J, Carroll J.) J Opt Soc Am A Opt Image Sci Vis. 2021 Oct 01;38(10):1400-1408 PMID: 34612970 PMCID: PMC8647682 SCOPUS ID: 2-s2.0-85116338744 10/07/2021

• ATF6 is essential for human cone photoreceptor development.

  (Kroeger H, Grandjean JMD, Chiang WJ, Bindels DD, Mastey R, Okalova J, Nguyen A, Powers ET, Kelly JW, Grimsey NJ, Michaelides M, Carroll J, Wiseman RL, Lin JH.) Proc Natl Acad Sci U S A. 2021 09 28;118(39) PMID: 34561305 PMCID: PMC8488632 SCOPUS ID: 2-s2.0-85117051646 09/26/2021

• Pre-retinal delivery of recombinant adeno-associated virus vector significantly improves retinal transduction efficiency.

  (Zhang H, Sajdak BS, Merriman DK, Carroll J, Lipinski DM.) Mol Ther Methods Clin Dev. 2021 Sep 10;22:96-106 PMID: 34485598 PMCID: PMC8390453 09/07/2021

• Development of a Preclinical Laser Speckle Contrast Imaging Instrument for Assessing Systemic and Retinal Vascular Function in Small Rodents.

  (Patel DD, Dhalla AH, Viehland C, Connor TB, Lipinski DM.) Transl Vis Sci Technol. 2021 08 02;10(9):19 PMID: 34403474 PMCID: PMC8374978 SCOPUS ID: 2-s2.0-85114392221 08/18/2021

• Optical Coherence Tomography Angiography in the Thirteen-Lined Ground Squirrel.

  (Salmon AE, Chen RC, Atry F, Gaffney M, Merriman DK, Gil DA, Skala MC, Collery R, Allen KP, Buckland E, Pashaie R, Carroll J.) Transl Vis Sci Technol. 2021 07 01;10(8):5 PMID: 34232271 PMCID: PMC8267221 SCOPUS ID: 2-s2.0-85111034709 07/08/2021

• Retinal alterations in patients with Lafora disease

  (Heitkotter H, Linderman RE, Cava JA, Woertz EN, Mastey RR, Summerfelt P, Chui TY, Rosen RB, Patterson EJ, Vincent A, Carroll J, Minassian BA.) American Journal of Ophthalmology Case Reports. September 2021;23 SCOPUS ID: 2-s2.0-85108265763 09/01/2021

• Disruption of foxc1 genes in zebrafish results in dosage-dependent phenotypes overlapping Axenfeld-Rieger syndrome.

  (Ferre-Fernández JJ, Sorokina EA, Thompson S, Collery RF, Nordquist E, Lincoln J, Semina EV.) Hum Mol Genet. 2020 09 29;29(16):2723-2735 PMID: 32720677 PMCID: PMC7530528 SCOPUS ID: 2-s2.0-85092681312 07/29/2020

• Noninvasive Imaging of Cone Ablation and Regeneration in Zebrafish.

  (Huckenpahler AL, Lookfong NA, Warr E, Heffernan E, Carroll J, Collery RF.) Transl Vis Sci Technol. 2020 09;9(10):18 PMID: 32983626 PMCID: PMC7500127 SCOPUS ID: 2-s2.0-85091664660 09/29/2020

• Electroretinogram of the Cone-Dominant Thirteen-Lined Ground Squirrel during Euthermia and Hibernation in Comparison with the Rod-Dominant Brown Norway Rat.

  (Zhang H, Sajdak BS, Merriman DK, McCall MA, Carroll J, Lipinski DM.) Invest Ophthalmol Vis Sci. 2020 06 03;61(6):6 PMID: 32492111 PMCID: PMC7415905 SCOPUS ID: 2-s2.0-85085963234 06/04/2020

• Validating a low-cost laser speckle contrast imaging system as a quantitative tool for assessing retinal vascular function.

  (Patel DD, Lipinski DM.) Sci Rep. 2020 04 28;10(1):7177 PMID: 32346043 PMCID: PMC7188677 04/30/2020

• Dynamic Polarization of Rab11a Modulates Crb2a Localization and Impacts Signaling to Regulate Retinal Neurogenesis.

  (Clark BS, Miesfeld JB, Flinn MA, Collery RF, Link BA.) Front Cell Dev Biol. 2020;8:608112 PMID: 33634099 PMCID: PMC7900515 SCOPUS ID: 2-s2.0-85101223534 02/27/2021

• Presynaptic Expression of LRIT3 Transsynaptically Organizes the Postsynaptic Glutamate Signaling Complex Containing TRPM1.

  (Hasan N, Pangeni G, Cobb CA, Ray TA, Nettesheim ER, Ertel KJ, Lipinski DM, McCall MA, Gregg RG.) Cell Rep. 2019 06 11;27(11):3107-3116.e3 PMID: 31189098 PMCID: PMC6628893 06/13/2019

• Acid Ceramidase Deficiency in Mice Leads to Severe Ocular Pathology and Visual Impairment.

  (Yu FPS, Sajdak BS, Sikora J, Salmon AE, Nagree MS, Gurka J, Kassem IS, Lipinski DM, Carroll J, Medin JA.) Am J Pathol. 2019 02;189(2):320-338 PMID: 30472209 PMCID: PMC6412726 SCOPUS ID: 2-s2.0-85060099082 11/26/2018

• Precise Short Sequence Insertion in Zebrafish Using a CRISPR/Cas9 Approach to Generate a Constitutively Soluble Lrp2 Protein.

  (Collery RF, Link BA.) Front Cell Dev Biol. 2019;7:167 PMID: 31457013 PMCID: PMC6700241 SCOPUS ID: 2-s2.0-85072723134 08/29/2019

• Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation.

  (Hanovice NJ, Leach LL, Slater K, Gabriel AE, Romanovicz D, Shao E, Collery R, Burton EA, Lathrop KL, Link BA, Gross JM.) PLoS Genet. 2019 01;15(1):e1007939 PMID: 30695061 PMCID: PMC6368336 SCOPUS ID: 2-s2.0-85061272556 01/30/2019

• A Comparison of Inducible Gene Expression Platforms: Implications for Recombinant Adeno-Associated Virus (rAAV) Vector-Mediated Ocular Gene Therapy.

  (Lipinski DM.) Adv Exp Med Biol. 2019;1185:79-83 PMID: 31884592 12/31/2019

• A Destabilizing Domain Allows for Fast, Noninvasive, Conditional Control of Protein Abundance in the Mouse Eye - Implications for Ocular Gene Therapy.

  (Datta S, Renwick M, Chau VQ, Zhang F, Nettesheim ER, Lipinski DM, Hulleman JD.) Invest Ophthalmol Vis Sci. 2018 10 01;59(12):4909-4920 PMID: 30347085 PMCID: PMC6181441 10/23/2018

• Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD.

  (Reid CA, Nettesheim ER, Connor TB, Lipinski DM.) Sci Rep. 2018 08 06;8(1):11763 PMID: 30082848 PMCID: PMC6079038 SCOPUS ID: 2-s2.0-85051247613 08/08/2018

• Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography.

  (Lapierre-Landry M, Huckenpahler AL, Link BA, Collery RF, Carroll J, Skala MC.) Transl Vis Sci Technol. 2018;7(5):4 PMID: 30197836 PMCID: PMC6126953 09/11/2018

• Brain-Derived Neurotrophic Factor as a Treatment Option for Retinal Degeneration.

  (Daly C, Ward R, Reynolds AL, Galvin O, Collery RF, Kennedy BN.) Adv Exp Med Biol. 2018;1074:465-471 PMID: 29721977 SCOPUS ID: 2-s2.0-85046643012 05/04/2018

• Repeatability and Reproducibility of In Vivo Cone Density Measurements in the Adult Zebrafish Retina.

  (Huckenpahler A, Wilk M, Link B, Carroll J, Collery R.) Adv Exp Med Biol. 2018;1074:151-156 PMID: 29721939 PMCID: PMC6363109 SCOPUS ID: 2-s2.0-85046645800 05/04/2018

• Improvement of Photoreceptor Targeting via Intravitreal Delivery in Mouse and Human Retina Using Combinatory rAAV2 Capsid Mutant Vectors.

  (Reid CA, Ertel KJ, Lipinski DM.) Invest Ophthalmol Vis Sci. 2017 12 01;58(14):6429-6439 PMID: 29260200 PMCID: PMC5736327 12/21/2017

• The Effect of Retinal Melanin on Optical Coherence Tomography Images.

  (Wilk MA, Huckenpahler AL, Collery RF, Link BA, Carroll J.) Transl Vis Sci Technol. 2017 Apr;6(2):8 PMID: 28392975 PMCID: PMC5381330 04/11/2017

• Imaging the adult zebrafish cone mosaic using optical coherence tomography-CORRIGENDUM.

  (Huckenpahler AL, Wilk MA, Cooper RF, Moehring F, Link BA, Carroll J, Collery RF.) Vis Neurosci. 2017 01;34:E005 PMID: 28965523 PMCID: PMC8054337 SCOPUS ID: 2-s2.0-85057402023 10/03/2017