Ophthalmology and Visual Sciences

Recent Publications

• The relationship between retinal cone density and cortical magnification in human albinism.

  (Woertz EN, Wilk MA, Duwell EJ, Mathis JR, Carroll J, DeYoe EA.) J Vis. 2020 Jun 03;20(6):10 PMID: 32543650 SCOPUS ID: 2-s2.0-85086624344 06/17/2020

• Electroretinogram of the Cone-Dominant Thirteen-Lined Ground Squirrel during Euthermia and Hibernation in Comparison with the Rod-Dominant Brown Norway Rat.

  (Zhang H, Sajdak BS, Merriman DK, McCall MA, Carroll J, Lipinski DM.) Invest Ophthalmol Vis Sci. 2020 Jun 03;61(6):6 PMID: 32492111 SCOPUS ID: 2-s2.0-85085963234 06/04/2020

• Visual Acuity and Foveal Structure in Eyes with Fragmented Foveal Avascular Zones.

  (Linderman RE, Cava JA, Salmon AE, Chui TY, Marmorstein AD, Lujan BJ, Rosen RB, Carroll J.) Ophthalmol Retina. 2020 05;4(5):535-544 PMID: 31956075 PMCID: PMC7211138 01/21/2020

• Validating a low-cost laser speckle contrast imaging system as a quantitative tool for assessing retinal vascular function.

  (Patel DD, Lipinski DM.) Sci Rep. 2020 Apr 28;10(1):7177 PMID: 32346043 PMCID: PMC7188677 04/30/2020

• Multiexon deletion alleles of ATF6 linked to achromatopsia.

  (Lee EJ, Chiang WJ, Kroeger H, Bi CX, Chao DL, Skowronska-Krawczyk D, Mastey RR, Tsang SH, Chea L, Kim K, Lambert SR, Grandjean JM, Baumann B, Audo I, Kohl S, Moore AT, Wiseman RL, Carroll J, Lin JH.) JCI Insight. 2020 Apr 09;5(7) PMID: 32271167 PMCID: PMC7205249 SCOPUS ID: 2-s2.0-85085324262 04/10/2020

• Quantitative proteomic analysis of aqueous humor after rabbit lensectomy reveals differences in coagulation and immunomodulatory proteins.

  (Young JB, Keppel TR, Waas M, Salmon AE, Buchberger AR, Skumatz CMB, Gundry RL, Kassem IS.) Mol Omics. 2020 04 01;16(2):126-137 PMID: 32031200 SCOPUS ID: 2-s2.0-85083358728 02/08/2020

• Interocular Symmetry of Foveal Cone Topography in Congenital Achromatopsia.

  (Litts KM, Georgiou M, Langlo CS, Patterson EJ, Mastey RR, Kalitzeos A, Linderman RE, Lam BL, Fishman GA, Pennesi ME, Kay CN, Hauswirth WW, Michaelides M, Carroll J.) Curr Eye Res. 2020 Mar 13:1-8 PMID: 32108519 SCOPUS ID: 2-s2.0-85081741600 02/29/2020

• Photoreceptor Structure in GNAT2-Associated Achromatopsia.

  (Georgiou M, Singh N, Kane T, Robson AG, Kalitzeos A, Hirji N, Webster AR, Dubra A, Carroll J, Michaelides M.) Invest Ophthalmol Vis Sci. 2020 03 09;61(3):40 PMID: 32203983 SCOPUS ID: 2-s2.0-85082284954 03/24/2020

• Assessing Ganglion Cell Layer Topography in Human Albinism Using Optical Coherence Tomography.

  (Woertz EN, Omoba BS, Dunn TM, Chiu SJ, Farsiu S, Strul S, Summers CG, Drack AV, Carroll J.) Invest Ophthalmol Vis Sci. 2020 03 09;61(3):36 PMID: 32196097 SCOPUS ID: 2-s2.0-85082147474 03/21/2020

• Interocular asymmetry of foveal avascular zone morphology and parafoveal capillary density in sickle cell retinopathy.

  (Zhou DB, Scott AW, Linz MO, Han IC, Castanos MV, Lynch G, Andrade Romo JS, Linderman RE, Carroll J, Rosen RB, Chui TY.) PLoS One. 2020;15(6):e0234151 PMID: 32520956 PMCID: PMC7286490 SCOPUS ID: 2-s2.0-85086356470 06/11/2020

• Deep Phenotyping of PDE6C-Associated Achromatopsia.

  (Georgiou M, Robson AG, Singh N, Pontikos N, Kane T, Hirji N, Ripamonti C, Rotsos T, Dubra A, Kalitzeos A, Webster AR, Carroll J, Michaelides M.) Invest Ophthalmol Vis Sci. 2019 12 02;60(15):5112-5123 PMID: 31826238 PMCID: PMC6905659 SCOPUS ID: 2-s2.0-85076396804 12/12/2019

• Assessing the Use of Incorrectly Scaled Optical Coherence Tomography Angiography Images in Peer-Reviewed Studies: A Systematic Review.

  (Llanas S, Linderman RE, Chen FK, Carroll J.) JAMA Ophthalmol. 2019 Nov 27 PMID: 31774456 SCOPUS ID: 2-s2.0-85075795857 11/28/2019

• Noninvasive Imaging and Correlative Histology of Cone Photoreceptor Structure in the Pig Retina.

  (Huckenpahler AL, Carroll J, Salmon AE, Sajdak BS, Mastey RR, Allen KP, Kaplan HJ, McCall MA.) Transl Vis Sci Technol. 2019 Nov;8(6):38 PMID: 31867139 PMCID: PMC6922271 12/24/2019

• Assessing the Interocular Symmetry of Foveal Outer Nuclear Layer Thickness in Achromatopsia.

  (Mastey RR, Gaffney M, Litts KM, Langlo CS, Patterson EJ, Strampe MR, Kalitzeos A, Michaelides M, Carroll J.) Transl Vis Sci Technol. 2019 Sep;8(5):21 PMID: 31602346 PMCID: PMC6779097 10/12/2019

• Zone of retinal vascularization and refractive error in premature eyes with and without spontaneously regressed retinopathy of prematurity.

  (Dikopf MS, Machen LA, Hallak JA, Chau FY, Kassem IS.) J AAPOS. 2019 08;23(4):211.e1-211.e6 PMID: 31229607 PMCID: PMC6778011 SCOPUS ID: 2-s2.0-85070210736 06/24/2019

• Managing a Slipped Muscle Following an Adjustable Suture Medial Rectus Recession.

  (Dotan G, Kassem I, Weaver D, Wagner RS.) J Pediatr Ophthalmol Strabismus. 2019 07 01;56(4):209-211 PMID: 31322707 SCOPUS ID: 2-s2.0-85070099756 07/20/2019

• Rats deficient in α-galactosidase A develop ocular manifestations of Fabry disease.

  (Miller JJ, Aoki K, Reid CA, Tiemeyer M, Dahms NM, Kassem IS.) Sci Rep. 2019 06 28;9(1):9392 PMID: 31253878 PMCID: PMC6599056 SCOPUS ID: 2-s2.0-85068107461 06/30/2019

• Presynaptic Expression of LRIT3 Transsynaptically Organizes the Postsynaptic Glutamate Signaling Complex Containing TRPM1.

  (Hasan N, Pangeni G, Cobb CA, Ray TA, Nettesheim ER, Ertel KJ, Lipinski DM, McCall MA, Gregg RG.) Cell Rep. 2019 06 11;27(11):3107-3116.e3 PMID: 31189098 PMCID: PMC6628893 06/13/2019

• Sustained Anti-Vascular Endothelial Growth Factor Activity of Aflibercept (Eylea) After Storage in Polycarbonate Syringes Used for Intravitreal Injection: A Pathway to Safety and Efficiency.

  (Han DP, Skumatz C, Besharse JC, Kassem IS.) J Ocul Pharmacol Ther. 2019 06;35(5):278-282 PMID: 30916605 PMCID: PMC6588124 SCOPUS ID: 2-s2.0-85067020226 03/28/2019

• Acid Ceramidase Deficiency in Mice Leads to Severe Ocular Pathology and Visual Impairment.

  (Yu FPS, Sajdak BS, Sikora J, Salmon AE, Nagree MS, Gurka J, Kassem IS, Lipinski DM, Carroll J, Medin JA.) Am J Pathol. 2019 02;189(2):320-338 PMID: 30472209 PMCID: PMC6412726 SCOPUS ID: 2-s2.0-85060099082 11/26/2018

• Interocular symmetry, intraobserver repeatability, and interobserver reliability of cone density measurements in the 13-lined ground squirrel.

  (Sajdak BS, Salmon AE, Linderman RE, Cava JA, Heitkotter H, Carroll J.) PLoS One. 2019;14(9):e0223110 PMID: 31557245 PMCID: PMC6762077 SCOPUS ID: 2-s2.0-85072655047 09/27/2019

• Precise Short Sequence Insertion in Zebrafish Using a CRISPR/Cas9 Approach to Generate a Constitutively Soluble Lrp2 Protein.

  (Collery RF, Link BA.) Front Cell Dev Biol. 2019;7:167 PMID: 31457013 PMCID: PMC6700241 SCOPUS ID: 2-s2.0-85072723134 08/29/2019

• Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation.

  (Hanovice NJ, Leach LL, Slater K, Gabriel AE, Romanovicz D, Shao E, Collery R, Burton EA, Lathrop KL, Link BA, Gross JM.) PLoS Genet. 2019 01;15(1):e1007939 PMID: 30695061 PMCID: PMC6368336 SCOPUS ID: 2-s2.0-85061272556 01/30/2019

• Use of a Juvenile Rabbit Animal Model to Evaluate Therapeutic Interventions for Postoperative Inflammation and Fibrin Formation After Lensectomy.

  (Bogaard JD, Young JB, Movahedan A, Kassem IS.) Transl Vis Sci Technol. 2019 Jan;8(1):5 PMID: 30637175 PMCID: PMC6327344 01/15/2019

• A Comparison of Inducible Gene Expression Platforms: Implications for Recombinant Adeno-Associated Virus (rAAV) Vector-Mediated Ocular Gene Therapy.

  (Lipinski DM.) Adv Exp Med Biol. 2019;1185:79-83 PMID: 31884592 12/31/2019

• A Destabilizing Domain Allows for Fast, Noninvasive, Conditional Control of Protein Abundance in the Mouse Eye - Implications for Ocular Gene Therapy.

  (Datta S, Renwick M, Chau VQ, Zhang F, Nettesheim ER, Lipinski DM, Hulleman JD.) Invest Ophthalmol Vis Sci. 2018 10 01;59(12):4909-4920 PMID: 30347085 PMCID: PMC6181441 10/23/2018

• Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD.

  (Reid CA, Nettesheim ER, Connor TB, Lipinski DM.) Sci Rep. 2018 08 06;8(1):11763 PMID: 30082848 PMCID: PMC6079038 SCOPUS ID: 2-s2.0-85051247613 08/08/2018

• Findings in Persistent Retinopathy of Prematurity.

  (Warren CC, Young JB, Goldberg MR, Connor TB, Kassem IS, Costakos DM.) Ophthalmic Surg Lasers Imaging Retina. 2018 07 01;49(7):497-503 PMID: 30021036 PMCID: PMC6196355 SCOPUS ID: 2-s2.0-85050358307 07/19/2018

• Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography.

  (Lapierre-Landry M, Huckenpahler AL, Link BA, Collery RF, Carroll J, Skala MC.) Transl Vis Sci Technol. 2018;7(5):4 PMID: 30197836 PMCID: PMC6126953 09/11/2018

• Brain-Derived Neurotrophic Factor as a Treatment Option for Retinal Degeneration.

  (Daly C, Ward R, Reynolds AL, Galvin O, Collery RF, Kennedy BN.) Adv Exp Med Biol. 2018;1074:465-471 PMID: 29721977 SCOPUS ID: 2-s2.0-85046643012 05/04/2018

• Repeatability and Reproducibility of In Vivo Cone Density Measurements in the Adult Zebrafish Retina.

  (Huckenpahler A, Wilk M, Link B, Carroll J, Collery R.) Adv Exp Med Biol. 2018;1074:151-156 PMID: 29721939 PMCID: PMC6363109 SCOPUS ID: 2-s2.0-85046645800 05/04/2018

• Findings in Persistent Retinopathy of Prematurity

  (Warren CC, Young JB, Goldberg MR, Connor TB, Kassem IS, Costakos DM.) Ophthalmic Surgery, Lasers, and Imaging Retina.. 05/09/2018

• Small and Micro-Scale Recombinant Adeno-Associated Virus Production and Purification for Ocular Gene Therapy Applications.

  (Reid CA, Lipinski DM.) Methods Mol Biol. 2018;1715:19-31 PMID: 29188503 12/01/2017

• Improvement of Photoreceptor Targeting via Intravitreal Delivery in Mouse and Human Retina Using Combinatory rAAV2 Capsid Mutant Vectors.

  (Reid CA, Ertel KJ, Lipinski DM.) Invest Ophthalmol Vis Sci. 2017 12 01;58(14):6429-6439 PMID: 29260200 PMCID: PMC5736327 12/21/2017

• miRNA-mediated post-transcriptional silencing of transgenes leads to increased adeno-associated viral vector yield and targeting specificity.

  (Reid CA, Boye SL, Hauswirth WW, Lipinski DM.) Gene Ther. 2017 08;24(8):462-469 PMID: 28617420 06/16/2017

• Biometry Characteristics in Adults and Children With Marfan Syndrome: From the Marfan Eye Consortium of Chicago.

  (Kinori M, Wehrli S, Kassem IS, Azar NF, Maumenee IH, Mets MB.) Am J Ophthalmol. 2017 May;177:144-149 PMID: 28257833 PMCID: PMC5648325 SCOPUS ID: 2-s2.0-85015385280 03/05/2017

• The Effect of Retinal Melanin on Optical Coherence Tomography Images.

  (Wilk MA, Huckenpahler AL, Collery RF, Link BA, Carroll J.) Transl Vis Sci Technol. 2017 Apr;6(2):8 PMID: 28392975 PMCID: PMC5381330 04/11/2017

• Imaging the adult zebrafish cone mosaic using optical coherence tomography-CORRIGENDUM.

  (Huckenpahler AL, Wilk MA, Cooper RF, Moehring F, Link BA, Carroll J, Collery RF.) Vis Neurosci. 2017 01;34:E005 PMID: 28965523 SCOPUS ID: 2-s2.0-85057402023 10/03/2017

• Loss of Zebrafish Mfrp Causes Nanophthalmia, Hyperopia, and Accumulation of Subretinal Macrophages.

  (Collery RF, Volberding PJ, Bostrom JR, Link BA, Besharse JC.) Invest Ophthalmol Vis Sci. 2016 12 01;57(15):6805-6814 PMID: 28002843 PMCID: PMC5215506 SCOPUS ID: 2-s2.0-85007349845 12/22/2016

• Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo.

  (De Silva SR, Charbel Issa P, Singh MS, Lipinski DM, Barnea-Cramer AO, Walker NJ, Barnard AR, Hankins MW, MacLaren RE.) Gene Ther. 2016 11;23(11):767-774 PMID: 27416076 PMCID: PMC5097463 11/04/2016

• Engineering a Light-Attenuating Artificial Iris.

  (Shareef FJ, Sun S, Kotecha M, Kassem I, Azar D, Cho M.) Invest Ophthalmol Vis Sci. 2016 Apr 01;57(4):2195-202 PMID: 27116547 PMCID: PMC4849870 SCOPUS ID: 2-s2.0-84964770541 04/27/2016

• Imaging the adult zebrafish cone mosaic using optical coherence tomography.

  (Huckenpahler AL, Wilk MA, Cooper RF, Moehring F, Link BA, Carroll J, Collery RF.) Vis Neurosci. 2016 01;33:E011 PMID: 28177275 PMCID: PMC5659228 SCOPUS ID: 2-s2.0-85020503535 02/09/2017

• A Case Report of Ablepharon-Macrostomia Syndrome with Amniotic Membrane Grafting.

  (Feinstein E, Traish AS, Aakalu V, Kassem IS.) Case Rep Ophthalmol. 2015 Sep-Dec;6(3):366-72 PMID: 26600791 PMCID: PMC4649710 11/26/2015

• Zebrafish Models of Retinal Disease.

  (Link BA, Collery RF.) Annu Rev Vis Sci. 2015 Nov 24;1:125-153 PMID: 28532376 11/24/2015

• Systemic Vascular Transduction by Capsid Mutant Adeno-Associated Virus After Intravenous Injection.

  (Lipinski DM, Reid CA, Boye SL, Peterson JJ, Qi X, Boye SE, Boulton ME, Hauswirth WW.) Hum Gene Ther. 2015 Nov;26(11):767-76 PMID: 26359319 PMCID: PMC4651034 09/12/2015

• Rapid, accurate, and non-invasive measurement of zebrafish axial length and other eye dimensions using SD-OCT allows longitudinal analysis of myopia and emmetropization.

  (Collery RF, Veth KN, Dubis AM, Carroll J, Link BA.) PLoS One. 2014;9(10):e110699 PMID: 25334040 PMCID: PMC4205002 SCOPUS ID: 2-s2.0-84908190382 10/22/2014

• Expression profiling of the RPE in zebrafish smarca4 mutant revealed altered signals that potentially affect RPE and retinal differentiation.

  (Zhang L, Ma P, Collery R, Trowbridge S, Zhang M, Zhong W, Leung YF.) Mol Vis. 2014;20:56-72 PMID: 24426776 PMCID: PMC3888495 SCOPUS ID: 2-s2.0-84891769215 01/16/2014