Research Studies at the Eye Institute

Research Studies at the Eye Institute Our mission is to improve, restore, and preserve sight. Research is an integral part of this mission. In fact, since its opening in 1976, the Eye Institute at Froedtert and the Medical College of Wisconsin has been committed to advancing our ability to provide excellent clinical and surgical care through investing in research. From developing novel surgical techniques, to participating in national clinical trials to test new drugs, to advancing state-of-the art imaging tools to study retinal disease, we remain at the forefront of vision research.

Our research team includes dozens of individuals here at the Eye Institute:  clinicians, ophthalmic technicians, clinic staff, research faculty, clinical research coordinators, ophthalmic photographers, and students - all of whom are committed to improving vision through research.

We are proud of our research history, and today we continue to be actively involved in a number of exciting research studies. Of course, our research would not be possible without the participation of research volunteers. Below you will find a list of research studies that are currently enrolling volunteers. If you think you qualify and would like more information or are interested in participating, please click the "I am interested" button next to that study.

Currently Enrolling Studies




IRB Approval

Horizon OPTIC Study for Thyroid Eye Disease
18-75 male female
Retrophin CTX Prevalence Cataract Study
  2 ▲ male female
MacTel Natural History Observation and Registry
for MacTel Type2
18 ▲ male female
Advanced Ocular Imaging:
Color Blindness
  5 ▲ male female


Ongoing Research Studies | Not Currently Enrolling




IRB Approval

Alcon-HAWK Study
for Wet AMD
50 ▲ male female
I am interested
Biomarkers Study
for Eye Disease
18 ▲ male female
I am interested


Closed Studies

Runge Card Study for Visual Acuity
TED01RV Study for Thyroid Eye Disease
Score 2 Study for Retinal Vein Occlusion
Acucela SEATTLE Study for Advanced Dry AMD
Allergan-PALM Study for Diabetic Macular Edema
Imaging Study for Dry and Wet AMD
Alkeus TEASE Study for Stargardt Disease

Research Studies FAQ

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  Why is research important?

Our mission - improving, restoring and preserving sight - reflects the purpose of an academic medical center. We combine patient care, vision research and education to accomplish our mission. Research studies are an important part of our mission because they help us learn about the eye in its normal and altered state. This knowledge can lead to improved patient care, therapies and treatments.

  What are clinical trials?

Nearly all major medical advances arose through clinical trials. Clinical trials examine new ways to prevent, diagnose, or treat disease. Treatments might use new drugs or a new combination of drugs, new surgical procedures or devices, or new ways to use existing treatments. The ultimate goal of most clinical trials is to determine if the new test or treatment is safe and whether it works.

  Why do people participate in research studies and clinical trials?

People participate in research for a number of reasons. Many people participate in order to help others and to contribute to moving our understanding of eye disease forward. Patients with an eye condition also might participate to help others in the future, but they may also participate to possibly receive the newest treatment and to have the additional care and attention from the research staff. Ultimately, the decision to participate in a research study is a personal one.

  Who can participate in these research studies?

All research studies have rules about who can and cannot participate. These are referred to as inclusion and exclusion criteria. These criteria may include factors such as age, gender, the type and severity of eye disease, whether they have received any previous treatments, and whether they have any other medical conditions.

Many types of people can participate in research studies. While most people who participate have some type of eye disease, many studies also include healthy volunteers. A healthy volunteer is someone who has no significant health problems. When developing a new tool, such as a new retinal imaging device, healthy volunteers can help researchers learn how well the device works. In clinical trials, healthy volunteers might serve as controls - they would receive the same test, procedure, or drug the patient group receives. Researchers can then learn a great deal by comparing the patient group with the healthy volunteers.

  How am I protected?

IRB review
All studies involving human research volunteers must be approved and monitored by an Institutional Review Board (IRB) to ensure that the volunteers who participate are treated ethically and are protected. An IRB is a committee that consists of medical professionals, non-medical professionals, and members of the community.

Informed consent
Before a potential research volunteer decides to participate in a study, it is important to ensure that they have been provided with all of the necessary information in order to make an informed decision. A member of the research team will explain the details of the study. They will review an informed consent document with you, which includes information about the purpose of the study, required procedures, and the potential risks and benefits associated with participating. This process of providing information will continue throughout the study.
If you decide to enroll in a study, the informed consent document will be signed. However, informed consent is not a contract. You are free to withdraw from the study at any time. If you decide to leave a study, you will not be penalized and will still be able to receive standard treatment appropriate for your eye condition.


Please call (414) 955-7910 to speak with our Clinical Research Coordinators.

Clinical Research Coordinators at the Eye Institute

Staff from the Office of Clinical and Translational Research (L to R) Katie McKenney, Pat Winter, Ellie Dorsey, Vesper Williams and Krissa Packard