Explore the most recent papers authored by the vision scientists and clinical faculty at the Medical College of Wisconsin.

Open AllClose All

Scoles, D., Sulai, Y.N., Cooper, R.F., Higgins, B.P., Johnson, R.D., Carroll, J., Dubra, A., Stepien, K.E. Photoreceptor Inner Segment Morphology in Best Vitelliform Macular Dystrophy. Retina, 37(4):741-748 (2017).

Han, D.P., McKenney, K.C., Kim, J.E., Weinberg, D.V., Musch, D.C., Singh, R.S. Clinical Evaluation of the Rapid Access Vitreal Injection Guide: A Handheld Instrument for Assisting Intravitreal Injections. Retina, 37(4):778-781 (2017).

Lewis, T.R., Kundinger, S.R., Pavlovich, A.L., Bostrom, J.R., Link, B.A., Besharse, J.C. Cos2/Kif7 and Osm-3/Kif17 regulate onset of outer segment development in zebrafish photoreceptors through distinct mechanisms. Developmental Biology, Epub ahead of print (2017).

Tee, J.J., Carroll, J., Webster, A.R., Michaelides, M. Quantitative analysis of retinal structure using spectral domain optical coherence tomography in RPGR-associated retinopathy. American Journal of Ophthalmology, Epub ahead of print (2017).

Marcos, S., Werner, J.S., Burns, S.A., Merigan, W.H., Artal, P., Atchison, D.A., Hampson, K.M., Legras, R., Lundstrom, L., Yoon, G., Carroll, J., Choi, S.S., Doble, N., Dubis, A.M., Dubra, A., Elsner, A., Jonnal, R., Miller, D.T., Paques, M., Smithson, H.E., Young, L.K., Zhang, Y., Campbell, M., Hunter, J., Metha, A., Palczewska, G., Schallek, J., Sincich, L.C. Vision science and adaptive optics, the state of the field. Vision Research, Epub ahead of print (2017).

Wilk, M.A., Dubis, A.M., Cooper, R.F., Summerfelt, P., Dubra, A., Carroll, J. Assessing the Spatial Relationship Between Fixation and Foveal Specializations. Vision Research, 132:53-61 (2017).

Dhakal, B., Fenske, T.S., Ramalingam, S., Shuff, J., Epperla, N., Hosking, P., Rein, L., Banerjee, A., Hari, P., D'Souza, A., Shah, N., Siker, M., Griepentrog, G.J., Harris, G.J., Wells, T.S., Erickson, B.A., Hamadani, M. Local Disease Control in Ocular Adnexal Lymphoproliferative Disorders: Comparative Outcomes of MALT Versus Non-MALT Histologies. Clinical Lymphoma, Myeloma & Leukemia, Epub ahead of print (2017).

Vogel, R.N., Davis, D.B., Kimura, B.H., Rathinavelu, S., Graves, G.S., Szabo, A., Han, D.P. Neovascular age-related macular degeneration with advanced visual loss treated with anti-vascular endothelial growth factor therapy: clinical outcome and prognostic indicators. Retina, 37(2): 257-264 (2017).

Langlo, C.S., Erker, L.R., Parker, M., Patterson, E.J., Higgins, B.P., Summerfelt, P., Razeen, M.M., Collison, F.T., Fishman, G.A., Kay, C.N., Zhang, J., Weleber, R.G., Yang, P., Pennesi, M.E., Lam, B.L., Chulay, J.D., Dubra, A., Hauswirth, W.W., Wilson, D.J., Carroll, J.; ACHM-001 study group. Repeatability and longitudinal assessment of foveal cone structure in CNGB3-associated achromatopsia. Retina, Epub ahead of print (2017).

Mo, S., Phillips, E., Krawitz, B.D., Garg, R., Salim, S., Geyman, L.S., Efstathiadis, E., Carroll, J., Rosen, R.B., Chui, T.Y. Visualization of radial peripapillary capillaries using optical coherence tomography angiography: the effect of image averaging. PLOS ONE 12(1): e0169385 (2017).

Vogel, R.N., Langlo, C.S., Scoles, D., Carroll, J., Weinberg, D.V., Kim, J.E. High-resolution imaging of intraretinal structures in active and resolved central serous chorioretinopathy. Investigative Ophthalmology & Visual Science, 58(1): 42-49 (2017).

Harris, G.J., Paul, S., Hunt, B.C. Oncocytic Adenocarcinoma of the Orbit. Ophthalmic Plastic and Reconstructive Surgery, 33(1):e18-e20 (2017).

Wilk, M.A., Wilk, B.M., Langlo, C.S., Cooper, R.F., Carroll, J. Evaluating Outer Segment Length as a Surrogate Measure of Peak Foveal Cone Density. Vision Research, 130: 57-66 (2017).

Wilk, M.A., Huckenpahler, A.L., Collery, R.F., Link, B.A., Carroll, J. The effect of retinal melanin on optical coherence tomography images. Translational Vision Science and Technology, In Press (2017).

Salmon, A.E., Cooper, R.F., Langlo, C.S., Baghaie, A., Dubra, A., Carroll, J. An automated reference frame selection (ARFS) algorithm for cone imaging with adaptive optics scanning light ophthalmoscopy. Translational Vision Science and Technology, In Press (2017).


Coca, M., Kim, J., Shenoy, S., Chévez-Barrios, P., Kapur, M. Microsporidial Stromal Keratitis: Successful Treatment with Topical Voriconazole and Oral Itraconazole. Cureus, 8(12):e934 (2016).

Sun, L.W., Johnson, R.D., Williams, V., Summerfelt, P., Dubra, A., Weinberg, D.V., Stepien, K.E., Fishman, G.A., Carroll, J. Multimodal Imaging of Photoreceptor Structure in Choroideremia. PLOS ONE, 11(12):e0167526 (2016).

Hove, M.N., Kilic-Biyik, K.Z., Trotter, A., Grønskov, K., Sander, B., Larsen, M., Carroll, J., Bech-Hansen, T., Rosenberg, T. Clinical characteristics, mutation spectrum, and prevalence of Åland eye disease/incomplete congenital stationary night blindness in Denmark. Investigative Ophthalmology & Visual Science, 57(15): 6861-6869 (2016).

Zareba, M., Widomska, J., Burke, J.M., Subczynski, W.K. Nitroxide free radicals protect macular carotenoids against chemical destruction (bleaching) during lipid peroxidation. Free Radical Biology & Medicine, 101:446-454 (2016).

Mainali, L., Raguz, M., O'Brien, W.J., Subczynski, W.K. Changes in the Properties and Organization of Human Lens Lipid Membranes Occurring with Age. Current Eye Research, Epub ahead of print (2016).

Wilson, M.A., Guld, K., Galetta, S., Walsh, R.D., Kharlip, J., Tamhankar, M., McGettigan, S., Schuchter, L.M., Fecher, L.A. Acute visual loss after ipilimumab treatment for metastatic melanoma. Journal for Immunotherapy of Cancer, 4:66 (2016).

Huckenpahler, A.L., Wilk, M.A., Cooper, R.F., Moehring, F., Link, B.A., Carroll, J., Collery, R.F. Imaging the adult zebrafish cone mosaic using optical coherence tomography. Visual Neuroscience, 33:E011 (2016).

Reis, L.M., Tyler, R.C., Weh, E., Hendee, K.E., Kariminejad, A., Abdul-Rahman, O., Ben-Omran, T., Manning, M.A., McCarty, C.A., Kitchner, T.E., Costakos, D., Semina, E.V. Analysis of CYP1B1 in pediatric and adult glaucoma and other ocular phenotypes. Molecular Vision, 22:1229-1238 (2016).

Wilson, D.J., Tasman, W.S., Skuta, G.L., Sheth, B.P. The Evolution of the American Board of Ophthalmology Written Qualifying Examination. Ophthalmology, 123(9 Suppl):S15-9 (2016).

Tam, J., Liu, J., Dubra, A., Fariss, R. In Vivo Imaging of the Human Retinal Pigment Epithelial Mosaic Using Adaptive Optics Enhanced Indocyanine Green Ophthalmoscopy. Investigative Ophthalmology & Visual Science, 57(10):4376-84 (2016).

Langlo, C.S., Patterson, E.J., Higgins, B.P., Summerfelt, P., Razeen, M.M., Erker, L.R., Parker, M., Collison, F.T., Fishman, G.A., Kay, C.N., Zhang, J., Weleber, R.G., Yang, P., Wilson, D.J., Pennesi, M.E., Lam, B.L., Chiang, J., Chulay, J.D., Dubra, A., Hauswirth, W.W., Carroll, J.; ACHM-001 Study Group. Residual Foveal Cone Structure in CNGB3-Associated Achromatopsia. Investigative Ophthalmology & Visual Science, 57(10):3984-95 (2016).

Chew, E.Y., Clemons, T.E., Harrington, M., Bressler, S.B., Elman, M.J., Kim, J.E., Garfinkel, R., Heier, J.S., Brucker, A., Boyer, D.; AREDS2-HOME Study Research Group. Effectiveness of Different Monitoring Modalities in the Detection of Neovascular Age-related Macular Degeneration: The Home Study, Report Number 3. Retina, 36(8):1542-7 (2016).

Happ, H., Schilter, K.F., Weh, E., Reis, L.M., Semina, E.V. 8q21.11 microdeletion in two patients with syndromic peters anomaly. American Journal of Medical Genetics Part A, 170(9):2471-5 (2016).

Patterson, E.J., Wilk, M., Langlo, C.S., Kasilian, M., Ring, M., Hufnagel, R.B., Dubis, A.M., Tee, J.J., Kalitzeos, A., Gardner, J.C., Ahmed, Z.M., Sisk, R.A., Larsen, M., Sjoberg, S., Connor, T.B., Dubra, A., Neitz, J., Hardcastle, A.J., Neitz, M., Michaelides, M., Carroll, J. Cone Photoreceptor Structure in Patients With X-Linked Cone Dysfunction and Red-Green Color Vision Deficiency. Investigative Ophthalmology & Visual Science, 57(8):3853-3863 (2016).

Mo, S., Krawitz, B., Efstathiadis, E., Geyman, L., Weitz, R., Chui, T.Y., Carroll, J., Dubra, A., Rosen, R.B. Imaging Foveal Microvasculature: Optical Coherence Tomography Angiography Versus Adaptive Optics Scanning Light Ophthalmoscope Fluorescein Angiography. Investigative Ophthalmology & Visual Science, 57(9):OCT130-40 (2016).

Reis, L.M., Tyler, R.C., Weh, E., Hendee, K.E., Schilter, K.F., Phillips III, J.A., Sequeira, S., Schinzel, A., Semina, E.V. Whole Exome Sequencing Identifies Multiple Diagnoses in Congenital Glaucoma with Systemic Anomalies. Clinical Genetics, 90(4):378-82 (2016).

Goldberg, M.R., Zakka, F.R., Carroll, J., Costakos, D.M. Attenuation of the Ganglion Cell Layer in a Premature Infant Revealed with Handheld Spectral Domain Optical Coherence Tomography. Retinal Cases & Brief Reports, 10(3):229-31 (2016).

Cooper, R.F., Wilk, M.A., Tarima, S., Carroll, J. Evaluating Descriptive Metrics of the Human Cone Mosaic. Investigative Ophthalmology & Visual Science, 57(7):2992-3001 (2016).

Besharse, J.C., McMahon, D.G. The Retina and Other Light-sensitive Ocular Clocks. Journal of Biological Rhythms, 31(3):223-43 (2016).

Jakobiec, F.A., Syed, Z.A., Stagner, A.M., Harris, G.J., Rootman, J., Yoon, M.K., Mombaerts, I. Orbital Inflammation in Pregnant Women. American Journal of Ophthalmology, 166:91-102 (2016).

Kim, J.E., Marmor, M.F. Update on Screening Recommendations for Hydroxychloroquine Retinopathy. JAMA Ophthalmology, 134(7):849 (2016).

Sun, L.W., Johnson, R.D., Langlo, C.S., Cooper, R.F., Razeen, M.M., Russillo, M.C., Dubra, A., Connor, T.B. Jr., Han, D.P., Pennesi, M.E., Kay, C.N., Weinberg, D.V., Stepien, K.E., Carroll, J. Assessing photoreceptor structure in retinitis pigmentosa and usher syndrome. Investigative Ophthalmology & Visual Science, 57(6):2428-42 (2016).

Chui, T.Y., Pinhas, A., Gan, A., Razeen, M.M., Shah, N., Cheang, E., Liu, C.L., Dubra, A., Rosen, R.B. Longitudinal imaging of microvascular remodeling in proliferative diabetic retinopathy using adaptive optics scanning light ophthalmoscopy. Ophthalmic & Physiological Optics, 36(3): 290-302 (2016).

Kim, J.E. Which Test Is the Best for Hydroxychloroquine Toxicity Screening? JAMA Ophthalmology, 134(5):520-521 (2016).

Cunefare, D., Cooper, R.F., Higgins, B., Katz, D.F., Dubra, A., Carroll, J., Farsiu, S. Automatic detection of cone photoreceptors in split detector adaptive optics scanning light ophthalmoscope images. Biomedical Optics Express, 7(5): 2036-2050 (2016).

Deml, B., Reis, L.M., Lemyre, E., Clark, R.D., Kariminejad, A., Semina, E.V. Novel mutations in PAX6, OTX2 and NDP in anophthalmia, microphthalmia and coloboma. European Journal of Human Genetics, 24(4):535-41 (2016).

Wei, L.A., Kennedy, T.A., Paul, S., Wells, T.S., Griepentrog, G.J., Lucarelli, M.J. Traumatic orbital encephalocele: Presentation and imaging. Orbit, 35(2): 72-7 (2016).

Subczynski, W.K., Mainali, L., Raguz, M., O'Brien, W.J. Organization of lipids in fiber-cell plasma membranes of the eye lens. Experimental Eye Research, Epub ahead of print (2016).

Brilliant, M.H., Vaziri, K., Connor, T.B. Jr., Schwartz, S.G., Carroll, J., McCarty, C.A., Schrodi, S.J., Hebbring, S.J., Kishor, K.S., Flynn, H.W. Jr., Moshfeghi, A.A., Moshfeghi, D.M., Fini, M.E., McKay, B.S. Mining retrospective data for virtual prospective drug repurposing: L-DOPA and age-related macular degeneration. The American Journal of Medicine, 129(3): 292-298 (2016).

Widomska, J., Zareba, M., Subczynski, W.K. Can Xanthophyll-Membrane Interactions Explain Their Selective Presence in the Retina and Brain? Foods, 5(1). pii: 7 (2016).

Razeen, M.M., Cooper, R.F., Langlo, C.S., Goldberg, M.R., Wilk, M.A., Han, D.P., Connor, T.B. Jr., Fishman, G.A., Collison, F.T., Sulai, Y.N., Dubra, A., Carroll, J., Stepien, K.E. Correlating photoreceptor mosaic structure to clinical findings in Stargardt disease. Translational Vision Science & Technology, 5(2): 6 eCollection (2016).

Cooper, R.F., Lombardo, M., Carroll, J., Sloan, K.R., Lombardo, G. Methods for investigating the local spatial anisotropy and the preferred orientation of cones in adaptive optics retinal images. Visual Neuroscience, 33: E005 (2016).

Cooper, R.F., Sulai, Y.N., Dubis, A.M., Chui, T.Y., Rosen, R.B., Michaelides, M., Dubra, A., Carroll, J. Effects of intraframe distortion on measures of cone mosaic geometry from adaptive optics scanning light ophthalmoscopy. Translational Vision Science & Technology, 5(1): 10 eCollection (2016).

Merriman, D.K., Sajdak, B.S., Li, W., Jones, B.W. Seasonal and post-trauma remodeling in cone-dominant ground squirrel retina. Experimental Eye Research, 150:90-105 (2016).

Warren, C.C., Liao, J.C., Griepentrog, G.J. Bilateral Extraocular Muscle Metastases From a Gastrointestinal Carcinoid Tumor. JAMA Ophthalmology, 134(1):e153651 (2016).

Abozaid, M.A., Langlo, C.S., Dubis, A.M., Michaelides, M., Tarima, S., Carroll, J. Reliability and repeatability of cone density measurements in patients with congenital achromatopsia. Advances in Experimental Medicine and Biology, 854: 277-283 (2016).

Aboshiha, J., Dubis, A.M., Carroll, J., Hardcastle, A., Michaelides, M. The cone dysfunction syndromes. British Journal of Ophthalmology, 100(1): 115-121 (2016).

Heier, J.S., Bressler, N.M., Avery, R.L., Bakri, S.J., Boyer, D.S., Brown, D.M., Dugel, P.U., Freund, K.B., Glassman, A.R., Kim, J.E., Martin, D.F., Pollack, J.S., Regillo, C.D., Rosenfeld, P.J., Schachat, A.P., Wells, J.A. 3rd. Comparison of Aflibercept, Bevacizumab, and Ranibizumab for Treatment of Diabetic Macular Edema: Extrapolation of Data to Clinical Practice. JAMA Ophthalmology, 134(1):95-9 (2016).

Esmaili, N., Harris, G.J. Langerhans Cell Histiocytosis of the Orbit: Spectrum of Disease and Risk of Central Nervous System Sequelae in Unifocal Cases. Ophthalmic Plastic and Reconstructive Surgery, 32(1):28-34 (2016).

Scoles, D., Flatter, J.A., Cooper, R.F., Langlo, C.S., Robison, S., Neitz, M., Weinberg, D.V., Pennesi, M.E., Han, D.P., Dubra, A., Carroll, J.  Assessing photoreceptor structure associated with ellipsoid zone disruptions visualized with optical coherence tomography. Retina, 36(1): 91-103 (2016).

Zhaoping, L., Carroll, J. An analytical model of the influence of cone sensitivity and numerosity on the Rayleigh match. Journal of the Optical Society of America, 33(3): A228-A237 (2016).

Sajdak, B.S., Sulai, Y.N., Langlo, C.S., Luna, G., Fisher, S.K., Merriman, D.K., Dubra, A. Noninvasive imaging of the thirteen-lined ground squirrel photoreceptor mosaic. Visual Neuroscience, 33: E003 (2016).