Mellowes Center Annual Rare Diseases and Rare Cancers in the Era of Systems Biology Symposium

The Mellowes Center 3rd annual Rare Diseases and Rare Cancers in the Era of Systems Biology Symposium was held November 12-13, 2025, as a two-day hybrid event featuring seminars and panel discussions from expert researchers and clinicians in four focus areas: From Mechanisms to Medicine in Mitochondrial Diseases, Diagnostic Discovery of Diseases, Human Diseases of the Epigenome, and Functional Modeling and Validation of Disease Variants.

Our symposium brought together regional and international speakers to explore the current landscape and future directions of rare disease and rare cancer research, advocating for greater understanding and expanded therapeutic interventions.

Marni Falk, MD, is an attending physician and Executive Director, Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia. She also holds the Distinguished Endowed Chair in the Department of Pediatrics and is a Professor, Division of Human Genetics, Department of Pediatrics, University of Pennsylvania Perelman School of Medicine. 

Danny Miller, MD, PhD , is an assistant professor in the Department of Pediatrics, Division of Genetic Medicine, and the Department of Laboratory Medicine and Pathology at the University of Washington and is an attending physician at Seattle Children's Hospital.