Krucoff Laboratory
Location
160F Cramer Hall
604 N. 16th St.
Milwaukee, WI 53233
General Interests
-Electrophysiological biomarkers of brain plasticity
-Neurophysiology of motor systems
-Brain control of hand movement
-Neural interfaces to improve function in central nervous system injury
-Neurorehabilitation
About the PI
Dr. Krucoff is a neurosurgeon-scientist on faculty in the Departments of Neurosurgery and Biomedical Engineering at the Medical College of Wisconsin and Marquette University. He received his Bachelor of Science (BS) in Biomedical Engineering from Northwestern University (NU) in Evanston, IL, and his Doctor of Medicine (MD) from George Washington University (GWU) in Washington, DC. Dr. Krucoff completed his neurosurgical residency at Duke University in Durham NC, where he received extensive training in brain tumor surgery from some of the biggest names in the field. Additionally, Dr. Krucoff underwent a year of specialized training in functional and epilepsy surgery at the University of California, San Francisco (UCSF), where he learned about the latest implantable bidirectional neural interfaces and brain mapping techniques. Dr. Krucoff's excellent surgical technique and bedside manner have been recognized by his mentors and peers, earning him the prestigious Surgical Excellence Award as a chief resident and election into the Alpha Omega Alpha (AOA) medical honor society as a medical student. As a neurosurgeon, Dr. Krucoff specializes in brain tumor operations that preserve critical neurological functions when they are at risk, like language and movement. He integrates the latest technological advancements with microscopic surgical technique to get the best outcomes for his patients, and his lab is set up to continue advancing what is possible when interacting with the human brain.
Dr. Krucoff’s post-graduate research career began at Northwestern University (NU) in Lee Miller, PhD’s lab where he served as a research technician learning about the dynamics of the primate motor cortex during limb movement. In medical school, Dr. Krucoff was one of 20 medical students nationwide awarded the 2010 American Academy of Neurology (AAN) Medical Student Research Scholarship to return to NU and work with Marc Slutzky, MD, PhD, on decoding hand movement from the human motor cortex with electrocorticography (ECoG). Later, while at Duke, Dr. Krucoff worked as a postdoctoral research associate in the lab of Miguel Nicolelis, MD, PhD, which included receiving an R25 grant from the National Institute of Neurological Disorders and Stroke (NINDS) to neural interfaces in non-human primates.
Dr. Krucoff's scientific pursuits have earned him widespread recognition, including election into the Robert J. Lefkowitz Society for physician-scientists at Duke University and the Tau Beta Pi (TBP) engineering honor society at Northwestern University, amongst others.
Dr. Krucoff currently lives in Wisconsin with his wife, Kate, and two daughters, Josephine and Maya. When he’s not at work or with his family, you can probably find him in his music studio playing the drums.
Read and watch more about Dr. Krucoff here:
MCW Neurosurgeon-Scientist Seeks to Unlock the Mysteries of the Brain Through Research with Tumors
Joining the Lab
Members of the Krucoff lab have unique opportunities to partner with consenting neurosurgical patients to learn more about how motor systems organize and reorganize in response to brain tumor growth, removal, and direct electrical stimulation. We partner with clinicians and scientists throughout the world in collaborative efforts to learn more about the physiology of human motor systems, and to improve outcomes for patients with central nervous system injuries by expanding what is possible.
Collaborating Labs
- Integrative Neural Engineering & Rehabilitation Laboratory, Marquette University. PI: Brian Schmit, PhD
- Laboratory of Neuromodulation & Neuroimaging, UCLA. PI: Nanthia Suthana, PhD
- Slutzky Neuroprosthetics Laboratory, Northwestern University. PI: Marc Slutzky, MD, PhD
- Yadav Lab, Indiana University. PI: Amol Yadav, PhD
- Lebedev Lab, Moscow, Russia. PI: Mikhail Lebedev, PhD
Current Projects
Current Members

Timothy Boerger, PhD
Postdoctoral Fellow, Department of Neurosurgery

Nada Botros
Medical Student

Brian Conway
Medical Student

Sarah Cornell
Research Coordinator

Edward Harwick
Medical Student

Leon Taquet
Engineer I
Krucoff Lab Image Gallery
Recent Publications
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(Harwick E, Singhal I, Conway B, Mueller W, Treffy R, Krucoff MO.) World Neurosurg. 2023 Jul;175:e159-e166 PMID: 36924891 SCOPUS ID: 2-s2.0-85152522605 03/17/2023
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Quantifying Hand Strength and Isometric Pinch Individuation Using a Flexible Pressure Sensor Grid.
(Conway BJ, Taquet L, Boerger TF, Young SC, Krucoff KB, Schmit BD, Krucoff MO.) Sensors (Basel). 2023 Jun 26;23(13) PMID: 37447773 PMCID: PMC10346473 SCOPUS ID: 2-s2.0-85164844180 07/14/2023
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Quantitative assessments of finger individuation with an instrumented glove.
(Conway BJ, Taquet L, Boerger TF, Young SC, Krucoff KB, Schmit BD, Krucoff MO.) J Neuroeng Rehabil. 2023 Apr 20;20(1):48 PMID: 37081513 PMCID: PMC10120262 SCOPUS ID: 2-s2.0-85153450611 04/21/2023
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(Popp N, Singhal I, Laing B, Krucoff KB, Krucoff MO.) . Neurosurgery Practice. 4(4):e00052, December 2023.. 12/01/2023
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(Boerger TF, Pahapill P, Butts AM, Arocho-Quinones E, Raghavan M, Krucoff MO.) Front Hum Neurosci. 2023;17:1170419 PMID: 37520929 PMCID: PMC10372448 SCOPUS ID: 2-s2.0-85165910739 07/31/2023
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(Taquet L, Conway BJ, Boerger TF, Young SC, Schwartz S, Schmit BD, Krucoff MO.) PLoS One. 2023;18(3):e0283460 PMID: 36972269 PMCID: PMC10042330 SCOPUS ID: 2-s2.0-85150987965 03/28/2023
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Approaches to the Cerebellopontine Angle
(Rahimpour S, Zomorodi AR, Codd PJ, Krucoff MO, Friedman AH, Gonzalez LF.) Surgery of the Cerebellopontine Angle, Second Edition. 1 January 2023:61-70 SCOPUS ID: 2-s2.0-85160174988 01/01/2023
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(Singhal I, Coss D, Mueller W, Straza M, Krucoff MO, Santos-Pinheiro F.) Front Oncol. 2022;12:1018840 PMID: 36568179 PMCID: PMC9771729 SCOPUS ID: 2-s2.0-85144424557 12/27/2022
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(Amidon RF, Santos-Pinheiro F, Straza M, Prah MA, Mueller WM, Krucoff MO, Connelly JM, Kleefisch CJ, Coss DJ, Cochran EJ, Bovi JA, Schultz CJ, Schmainda KM.) Front Oncol. 2022;12:1066191 PMID: 36561526 PMCID: PMC9763264 SCOPUS ID: 2-s2.0-85144231369 12/24/2022
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(Armstrong S, Prah M, Connelly J, Krucoff MO, Mueller W, Schmainda K.) Neuro-Oncology. Neuro-Oncology, Volume 24, Issue Supplement_7, November 2022, Page vii173 11/14/2022
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Editorial: Neuroplasticity in Rehabilitation.
(Krucoff MO, Cajigas I, Lavrov I.) Front Rehabil Sci. 2022;3:916174 PMID: 36189079 PMCID: PMC9397734 10/04/2022
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(Aaronson DM, Martinez Del Campo E, Boerger TF, Conway B, Cornell S, Tate M, Mueller WM, Chang EF, Krucoff MO.) Front Surg. 2021;8:730367 PMID: 34660677 PMCID: PMC8517489 SCOPUS ID: 2-s2.0-85117333999 10/19/2021