header-logo
Main Campus Entrance-MKE

Medical College of Wisconsin Neurosurgery Research

Research in MCW's Department of Neurosurgery includes three distinct research programs supporting multiple centers and laboratories at the Clement J. Zablocki VA Medical Center and MCW's Milwaukee campuses.

Our Research Mission

Our mission is to conduct innovative research that:

  • advances the science of neurotrauma and neurologic disease 
  • has a positive translational impact on clinical care 
  • fosters the development of scientists 
  • improves the health of our community

Our Research Vision

Our vision is to be a world-class center for neurotrauma research that positively impacts the lives of people affected by neurologic injury and disease.

Meier Lab_Intro-Component

Center for Neurotrauma Research

The Center for Neurotrauma Research seeks to advance the science of neurological trauma and related diseases, enhance the translation of brain and spinal trauma research into clinical care innovations, foster the professional development of future scientists, and improve the health of communities throughout the region and state. Within MCW, the CNTR functions as a collaborative hub for neurotrauma research and will create a synergistic collaboration with other MCW Centers such as the Comprehensive Injury Center, Neuroscience Research Center and the Center for Imaging Research.

MCW's Center for Neurotrauma Research is co-directed by Shekar Kurpad, MD, PhD, Sanford J. Larson Professor and Chair of Neurosurgery; and Michael McCrea, PhD, Professor of Neurosurgery, Eminent Scholar, Vice Chair of Research and Director of Brain Injury Research at the Medical College of Wisconsin. 



Vedantam Lab members discussing FEM modeling of discs in Hub for Collaborstive Medicine

Center for Cervical Myelopathy

The Center for Cervical Myelopathy aims to bridge the translational science spectrum to provide a uniquely well-rounded perspective on Cervical Myelopathy, an age-related degenerative disease of the cervical spinal cord resulting in pain and motor deficits. Specializing in a broad range of complimentary clinical and research methodologies, the assembled teams are positioned to advance diagnosis and treatment of Cervical Myelopathy at MCW, Froedtert, and beyond.

Neurosurgery Research Programs

Research from the Department of Neurosurgery includes multimodal investigations into the  generation and treatment of brain injury, biomechanics and spinal cord injury. 

Brain Imaging captured by the Meier Laboratory

Brain Injury Research 

The Brain Injury Research Program in MCW's Department of Neurosurgery includes investigations into the acute and chronic effects of traumatic brain injury.

Learn more about the Brain Injury Research Program
spine biomechanics-image card

Biomechanics Research

Neurosurgery Biomechanics research is carried out at the ZVAMC Labs and includes investigations into the biomechanics of trauma and biomechanics of the spine. 

Learn more about Biomechanics Research at ZVAMC Labs
SpineCare_Image Text Split Component

Spinal Cord Injury Research

Investigations into Spinal Cord Injury at the MCW Department of Neurosurgery seek to improve the recovery and quality of life for patients affected by acute and chronic SCI.   

Learn More about SCI Research at the Department of Neurosurgery

Neurosurgery Research Laboratories

Led by members of our world-class faculty, research laboratories at the Medical College of Wisconsin's Department of Neurosurgery specialize in a wide range of disciplines encompassing brain and spinal cord injury and trauma biomechanics. All have an end-goal of bettering the lives of individuals impacted by neurological disorder, injury, or disease. 

Budde Laboratory

Research image from Budde Lab

The Budde Lab develops and employs magnetic resonance imaging (MRI) as a tool to understand spinal cord biology and pathology.

Learn more about the Budde Lab

 

Gupta Laboratory

Macro imaging of neuronal pathways

The Gupta Lab studies the genes and molecular pathways responsible for the development of mesial temporal lobe epilepsy, the most common form of focal epilepsy.

Learn more about the Gupta Lab

 

Kroner Laboratory

Spine image

The Kroner Lab investigates tissue protection after spinal cord injury by interrupting inflammatory processes that promote tissue damage and neuronal death.

Learn more about the Kroner Lab

 

Krucoff Laboratory

Krucoff Lab logo

The Krucoff Lab investigates the physiology of human motor systems to improve outcomes for patients with central nervous system injuries.

Learn more about the Krucoff Lab

 

Kurpad Laboratory

CT image of the neck in black and white

The Kurpad Lab seeks a translational treatment approach to reduce secondary damage after injury and to improve quality of life after spinal cord injury.

Learn more about the Kurpad Lab

 

Meier Laboratory

Close-up Computer Generated Image of Brain Structure created by the Meier Lab

MCW's Meier Laboratory uses advanced imaging, clinical and behavioral testing to investigate the acute and chronic effects of traumatic brain injury. 

Learn more about Meier Lab

Nelson Laboratory

Brightly colored AI-generated rendering of brain

The Nelson Lab studies patients’ feeling and functioning after TBI to improve clinical endpoints, better understand patient heterogeneity, and develop patient-centered improvements in clinical care.   

Learn more about the Nelson Lab

 

NEMo Laboratory

Neural Engineering, Interfacing, Modulation & Optimization Lab at the Medical College of Wisconsin

The Neural Engineering & Modulation Lab develops novel neuroprosthetic and gene-therapy approaches to alleviate motor deficits caused by conditions such as SCI or amyotrophic lateral sclerosis. 

Learn more about the NEMo Lab

 

Rey Laboratory

ReyLab Logo

ReyLab develops new tools for data acquisition and analysis of electrophysiological data in the human brain through the use of advanced medical imaging, intracranial electroencephalography and single cell and local field potentials. 

Learn more about the ReyLab

 

Vedantam Laboratory

MR Cervical Spine Images from the Vedantam Lab, thumbMCW's Vedantam Laboratory seeks to improve the lives of people suffering from spinal cord dysfunction through investigations into the pathophysiology of disease states and recovery of function after injury.

Learn more about the Vedantam Lab

 

Yoganandan Laboratory

X-ray of cervical spine from Yoganandan Laboratory

The Yoganandan Lab develops personalized medicine for spinal disorders, develops response corridors and injury risk functions for the head and spine, and determine human head-spine responses under physiologic and traumatic loads.

Learn more about the Yoganandan Lab

 

 

Neurosurgery Research Facilities

The MCW Department of Neurosurgery supports its renowned neurosurgery research program with state-of-the-art facilities located on multiple campuses in the Greater Milwaukee area. 
all
The Hub for Collaborative Medicine on MCW's Milwaukee Campus
The Hub for Collaborative Medicine facilitates intersectional investigations with Froedtert Hospital and other Clinical Collaborators located on or near MCW's Milwaukee Campus. 
Biomechanics Research Facilities at ZVAMC Labs

The Biomechanics Research Facilities at the Zablocki VA Medical Center Laboratories support investigations into preclinical traumatic brain injury and biomechanics of trauma and the spine. Noteworthy capabilities include the Vehicle Crashworthiness facility, the Acceleration ServoSled facility, drop tower and pendulum facilities, electrohydraulic piston and blast test facilities, as well as computational modeling facilities. 

Learn more about Biomechanics Facilities at ZVAMC Labs

Neuroscience Research Facilities at ZVAMC Labs

The Neuroscience Research Facilities at ZVAMC Labs have been specially designed to support investigations into spinal cord injury and central nervous systems disorders.  Highlighted capabilities include rodent behavioral testing, small animal procedures, molecular biology, histology and microscopy, as well as electrophysiology and optogenetics. 

Learn more about Neuroscience Facilities at ZVAMC Labs