About OnCore

OnCore is the Clinical Trial Management Software (CTMS) developed by Forte Research and utilized by the Medical College of Wisconsin. OnCore is the most widely adopted clinical trial management system among academic research universities nationwide.

OnCore's initial rollout only included the MCW Cancer Center Clinical Trials Office and the Cardiovascular Clinical Trials. It is now available to all departments for their study management needs through the MCW Clinical Trials Office. The MCW Clinical Trials Office, in collaboration with Research Systems Training in the Office of Research, is responsible for training, providing access, troubleshooting, and continued support in utilizing OnCore at MCW. Although utilization of OnCore is currently optional for non-cancer trials, it is mandatory for all cancer trials.

The Medical College of Wisconsin provides research support services regarding the planning, implementation and financial management of clinical trials for investigators at MCW, MCW Cancer Center, Froedtert Hospital, Children’s Hospital of Wisconsin, the Zablocki VA Hospital, and the Blood Center of Wisconsin. With the aim to become a regional hub for clinical trials, the CTO will expand its services to the University of Wisconsin–Milwaukee, Marquette University and the Milwaukee School of Engineering. The CTO was created with the goal to become a one stop shop to provide research related resources for volunteers, sponsors, and research staff.

The MCW Clinical Trials Office is partnering with all MCW departments to implement OnCore. Contact the MCW CTO to Request a Consultation.

Register for an OnCore Account

In order to enter a new clinical trial into OnCore, investigators and study staff must be registered in OnCore. Please contact the OnCore Help Desk, oncore@mcw.edu, or by phone, (414) 955-8476, if you have any questions regarding registering, navigating, or entering information in the system. If your question pertains to a particular submission, please reference the Protocol name when calling the Help Desk.

OnCore Functionality

Click on a topic below to view the description of the OnCore feature. Or select the Open All link to view all the topics.

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Basic information associated with a particular protocol is recorded including protocol type, objectives, IRB and other committee reviews, research staff names and roles, and sponsor information.


Subject information for a particular protocol is recorded including demographics, consents signed, and milestone dates for:

  • On study
  • On treatment
  • Off treatment
  • On follow-up
  • Off study
  Protocol & Subject Calendar Management

Calendars maintain study parameters including treatment administration, evaluations, and data collection schedules. Subject-specific calendars are automatically generated for subject visit tracking which drives the financial management functionality.

  Subject Safety Management

Record AEs, SAEs, External Safety Reports and export to report to the IRB. Automatic safety notifications via email are configurable by protocol staff and/or role.

  User, Role, Study & Institutional Base Security

Users are assigned specific access role(s) and assigned to specific institutions and management groups in their OnCore account. Each protocol is associated with specific management groups, institutions, and staff. Taken together, this provides users with the access they require to work in OnCore on their specific protocols.

  Electronic Data Capture and Data Management

Electronic Case Report Forms (eCRFs) may be created and associated with particular subject visits in support of investigator initiated trials. eCRF data entry is easy to navigate with its status-organized tabs. For analysis, form data can be exported in MS Excel and SAS formats.

  Data Monitoring

Data monitor queries are available for section and/or field level within an eCRF.

  Biospecimen Management

Individual biospecimens can be tracked and monitored. Reporting capabilities exist at the individual sample or the biorepository level.


Standard and custom reports are available. Additionally there are search functions that allow queries on dozens of fields. Together, these features help pull information together about clinical research trials with an ease not previously available. Powerful reporting features can serve as a data-driven means for crafting operational and staffing decisions.

  Coverage Analysis/Billing Compliance
  • A "Qualifying Clinical Trial Checklist" is built into OnCore, providing the ability to store and report information for determining if a protocol meets requirements for insurance reimbursements.
  • Billing designations are defined at the procedure or visit level. The rationale behind the designations are documented in OnCore.
  • The billing grid is based on the protocol calendar/schedule of events and provides documentation of billing decisions, including routine cost designations and why the study is designated as a qualifying clinical trial.
  • Centralized storage for all documents relevant to the coverage analysis process.
  Financial Management

Financial management includes:

  • budget creation and negotiation
  • standard of care versus research-related charge delineation
  • milestone-based payments
  • automated invoicing rules
  • invoice creation
  • payment reconciliation

The financial functionality also includes the potential for importing an enterprise charge master.

  Staff Effort Tracking

Staff may track their effort during the life of a protocol through integrated functionality. Staff Effort Tracking and Reporting can assist with effective budgeting and negotiating for clinical trials, establishing performance benchmarks and supporting requests for increased resources.

  Study Information Portal

The Study Information Portal (SIP) supports a web-based interface for the general public to search and view protocol information in real-time and is tied directly to the OnCore database.

MCW Clinical Trials Office

(414) 805-6990

MCW Cancer Center
Clinical Trials Office
(414) 805-8900

Contact OnCore
Help Desk

Monday - Friday
8 a.m. - 5 p.m.

(414) 955-8476


Help Desk Service Request

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