Leading the Way in Discovering Novel Treatments for Pancreatic Cancer
Commitment to Research
The LaBahn Pancreatic Cancer Program supports internationally recognized specialists who provide a wealth of knowledge and experience in pancreatic cancer treatment and research. We are committed to developing the next generation of medical researchers and to translating our research into cutting-edge treatments for our patients. We are involved in many areas of research, including basic science, outcomes assessments, and international clinical trials. Our dedication to research is one of the many tools we have available to make MCW a destination for the best pancreatic cancer care possible.
About our Biorepository
Our biorepository is a phenomenal resource for both translational research collaborations as well as clinical outcomes research. The Ronald Burklund Eich integrated biorepository and database captures longitudinal samples from patients across a broad spectrum of disease, from pancreatic cancer screening to diagnosis, and even post-mortem.
Basic and Translational Scientific Investigators
Scientific investigators are discovery-drivers, working to uncover more innovative and cutting-edge treatments with every study they conduct.
Michael B. Dwinell, PhD
Professor; Founding Director, Center for Immunology; Director, Bobbie Nick Voss Laboratory for Colon Cancer Research; Hanis-Stepka-Rettig Endowed Chair in Cancer Research
Cancer Metastasis, Tumor Microenvironment, Mucosal Inflammation
Guan Chen, MD, PhD
Professor
Gwen Lomberk, PhD
Joel and Arlene Lee Chair in Pancreatic Cancer Research; Chief, Division of Research; Director, Basic Science Research, Department of Surgery; Professor of Surgery and Pharmacology & Toxicology
Nikki K. Lytle, PhD
Assistant Professor
Subramaniam Malarkannan, PhD
Professor and Gardetto Chair for Immunology and Immunotherapy; Professor, Medicine (Hematology and Oncology) and Microbiology & Immunology; Senior Investigator, Versiti Blood Research Institute
NK cell development and function
Thomas McFall, PhD
Assistant Professor
I am interested in experimental-systems approaches that enable mechanism-based inference in genomic medicine and can help identify patients for selective therapeutic strategies.
Jong-In Park, PhD
Professor; Eminent Scholar
Y. David Seo, MD
Assistant Professor
Raul A. Urrutia, MD
Professor, Department of Surgery; Director, Linda T. and John A. Mellowes Center for Genomic Sciences and Precision Medicine
Research Lab Links and More
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Department of Surgery- Division of Research
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Dr. Dwinell's Lab Page
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Dr. Lomberk's Lab Page
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Dr. Park's Lab Page
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Dr. Urrutia's Lab Page
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Recent Publications
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(Kamgar M, Hobbs GA, Davidson R, Dorbin D, Herrera J, Langenheim JF, Burge RA, Aldakkak M, Conrardy RD, Szabo A, Thalji SZ, Mayer B, Grahl JJ, Chung BY, Phan A, Thomas JP, Seo YD, Evans DB, Christians KK, Erickson B, Hall W, George B, Tsai S, Lytle NK, Der CJ, Kurzrock R, McFall T.) Cancer Res. 2025 Oct 24 PMID: 41134578 10/24/2025
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(Ayabe RI, Seo YD, Melendez B, Fields BC, Diggs LP, Lazcano R, Singh BB, Wani K, Ingram D, Johnson S, Chelvanambi M, Hudgens C, Hernandez SD, Ajami NJ, Wargo JA, Lazar AJ, Knafl M, Woodman S, Halperin DM, Estrella JS, Maxwell JE.) JCO Precis Oncol. 2025 Jul;9:e2500107 PMID: 40638874 PMCID: PMC12463141 07/10/2025
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(Drouillard D, Halyko M, Cinquegrani E, Poimenidou M, Emosivbe M, McAllister D, Peterson FC, Marchese A, Dwinell MB.) bioRxiv. 2025 Apr 14 PMID: 39253415 PMCID: PMC11383031 09/10/2024
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The triple code model for advancing research in rare and undiagnosed diseases beyond the base pairs
(Lomberk G, Urrutia R.) Epigenomics. 2025;17(2):115-124 SCOPUS ID: 2-s2.0-85210902607 01/01/2025
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(Abuelafia AM, Santofimia-Castaño P, Estaras M, Grasso D, Chuluyan E, Lomberk G, Urrutia R, Dusetti N, Fraunhoffer N, Iovanna J.) Translational Oncology. July 2025;57 SCOPUS ID: 2-s2.0-105005073485 07/01/2025
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ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity.
(Becker AE, Kochanowski P, Wu PK, Wątor E, Chen W, Guchhait K, Biela AP, Grudnik P, Park JI.) Cell Rep. 2024 Oct 22;43(10):114831 PMID: 39392755 PMCID: PMC11544350 SCOPUS ID: 2-s2.0-85207351264 10/11/2024
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(McFall T, Stites EC.) Cell Rep. 2021 Dec 14;37(11):110096 PMID: 34910921 PMCID: PMC8867612 SCOPUS ID: 2-s2.0-85121146579 12/16/2021