Leading the Way in Discovering Novel Treatments for Pancreatic Cancer
Commitment to Research
The LaBahn Pancreatic Cancer Program supports internationally recognized specialists who provide a wealth of knowledge and experience in pancreatic cancer treatment and research. We are committed to developing the next generation of medical researchers and to translating our research into cutting-edge treatments for our patients. We are involved in many areas of research, including basic science, outcomes assessments, and international clinical trials. Our dedication to research is one of the many tools we have available to make MCW a destination for the best pancreatic cancer care possible.
About our Biorepository
Our biorepository is a phenomenal resource for both translational research collaborations as well as clinical outcomes research. The Ronald Burklund Eich integrated biorepository and database captures longitudinal samples from patients across a broad spectrum of disease, from pancreatic cancer screening to diagnosis, and even post-mortem.
Basic and Translational Scientific Investigators
Scientific investigators are discovery-drivers, working to uncover more innovative and cutting-edge treatments with every study they conduct.
Michael B. Dwinell, PhD
Professor; Founding Director, Center for Immunology; Director, Bobbie Nick Voss Laboratory for Colon Cancer Research; Hanis-Stepka-Rettig Endowed Chair in Cancer Research
Cancer Metastasis, Tumor Microenvironment, Mucosal Inflammation
Guan Chen, MD, PhD
Professor
Nikki K. Lytle, PhD
Assistant Professor
Subramaniam Malarkannan, PhD
Professor and Gardetto Chair for Immunology and Immunotherapy; Professor, Medicine (Hematology and Oncology) and Microbiology & Immunology; Senior Investigator, Versiti Blood Research Institute
NK cell development and function
Thomas McFall, PhD
Assistant Professor
I am interested in experimental-systems approaches that enable mechanism-based inference in genomic medicine and can help identify patients for selective therapeutic strategies.
Jong-In Park, PhD
Professor; Eminent Scholar
Y. David Seo, MD
Assistant Professor
Research Lab Links and More
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Department of Surgery- Division of Research
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Dr. Dwinell's Lab Page
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Dr. Park's Lab Page
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Recent Publications
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The want for Wnt: Pancreatic cancer assembles a self-sustaining Wnt-signaling ecosystem.
(Lytle NK, Wood LD.) Dev Cell. 2026 May 13;61(5):971-972 PMID: 42127806 05/14/2026
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(Burge RA, Le Roux O, Popow O, Spadafora VK, Rajesh C, Adair SJ, Bialousow L, Murphy C, Saberi S, Vaena SG, Taquey MC, Allen S, Han L, Helke KL, Sharma S, Ostrowski MC, Guttridge DC, Dincman TA, Bauer TW, Kashatus DF, McFall T, Haigis KM, Hollingsworth MA, Counter CM, Der CJ, Hobbs GA.) Cancer Res. 2026 Apr 15;86(8):1868-1882 PMID: 41556816 PMCID: PMC13080325 SCOPUS ID: 2-s2.0-105035919044 01/20/2026
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(Dzikowski M, Pollin G, Gunia V, Butler S, Enkhtuul B, Gavina Chavez J, Zimmermann MT, Mathison A, Urrutia R, Lomberk G.) Front Cell Dev Biol. 2026;14:1748541 PMID: 41890907 PMCID: PMC13013501 SCOPUS ID: 2-s2.0-105033634422 03/27/2026
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(Salama AKS, Wang V, Macrae ER, Park JI, Chen HX, Gray RJ, McShane LM, Rubinstein LV, Patton D, Williams PM, Hamilton SR, Armstrong DK, Tricoli JV, Conley BA, Arteaga CL, Harris LN, O'Dwyer PJ, Chen AP, Flaherty KT.) JCO Precis Oncol. 2026 Jan;10:e2500338 PMID: 41533998 PMCID: PMC12810769 01/15/2026
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Biosafety assessment of engineered CCL20 locked dimers in vivo.
(Drouillard D, Poimenidou M, Davies M, McAllister D, Clarke WR, Hwang ST, Peterson FC, Volkman BF, Dwinell MB.) Cell Biol Toxicol. 2025 Dec 19;42(1):14 PMID: 41419693 PMCID: PMC12799736 SCOPUS ID: 2-s2.0-105027326723 12/20/2025
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(Ayabe RI, Seo YD, Melendez B, Fields BC, Diggs LP, Lazcano R, Singh BB, Wani K, Ingram D, Johnson S, Chelvanambi M, Hudgens C, Hernandez SD, Ajami NJ, Wargo JA, Lazar AJ, Knafl M, Woodman S, Halperin DM, Estrella JS, Maxwell JE.) JCO Precis Oncol. 2025 Jul;9:e2500107 PMID: 40638874 PMCID: PMC12463141 07/10/2025