Medical College of Wisconsin
Medical College of Wisconsin Medical College of Wisconsin
Research Bench Lab
Microbiology & Immunology

Dwinell Laboratory

Location

Microbiology & Immunology

TBRC C3860

General Interests

Cancer Progression and the Tumor Immune Microenvironment

View Michael B. Dwinell Bio
Michael Dwinell Laboratory
Frank-Licover_Image

Research Areas

My research has been investigating the cellular, biochemical, molecular and pathophysiologic mechanisms controlling cellular movement in inflammation and cancer. The movement of cells within and between tissues is a fundamental property of biology. Cell movement / migration, may have beneficial effects, for example in wound healing or leukocyte trafficking, or deleterious effects, such as in the invasion and metastasis of tumor cells. My laboratory uses a spectrum of cellular, molecular, metabolomic and biochemical techniques, in combination with an array of cell culture and preclinical transgenic mouse models, to dissect the details of how cells move and the functional consequences of that movement. As chemokines are the archetype immune molecules directing cell movement, the investigative focus of my research program is to resolve the mechanisms of chemokine signaling in order to improve human health through the design of new chemokine-targeted or immune targeted therapies to disrupt or promote cellular movement in inflammation and cancer.

Learn More

Dwinell Laboratory: Science Needs All of Us

Achieving important and productive science requires an inclusive team in which everyone is equal and mutually reinforcing the efforts of the entire group. The Dwinell laboratory continues to model and foster an equal, inclusive, diverse environment that respectfully promotes high quality science and excellent training. The Dwinell lab welcomes individuals from all groups and backgrounds to join our research team.

Research Support

Research in the Dwinell laboratory is supported through grants from the National Institutes of Health, long standing support from the Bobby Nick Voss Charitable Foundation, the Medical College of Wisconsin Cancer Center and philanthropic donations.

Current Members

headshot

Kathleen Boyle, PhD

Adjunct Assistant Professor

kboyle@mcw.edu

headshot

Donovan Drouillard

M2 Student

ddrouillard@mcw.edu

headshot

Peter Gandy

Visiting Scholar, Dwinell lab

pgandy@mcw.edu

headshot

Donna McAllister

Lab Supervisor

dmcallis@mcw.edu

headshot

Maria Poimenidou

Graduate Student

mpoimenidou@mcw.edu

headshot

Nathan Witman

Graduate Student

nwitman@mcw.edu

Recent Publications

Publications of Michael B. Dwinell PhD from the Faculty Collaboration Database

Learn More

Flashback

1 /
dwinell-lab-purple-for-pancreatic-cancer-day

2017

Wearing purple for World Pancreatic Cancer Day
Hide Caption
dwinelllab11

2013

Hide Caption
dwinelllabsm

2010

Hide Caption

Lab Alumni

Hong Guan, MS

Doctoral Candidate, Department of Chemistry and Biochemistry, University of South Carolina

 

Ishan Roy, MD, PhD

Clinical Instructor & Chief Resident Physician; Department of Physical Medicine & Rehabilitation, Northwestern University/Shirley Ryan Ability Lab

 

Natasha Moussouras, PhD

Research Fellow, Department of Microbiology & Immunology, Medical College of Wisconsin

 

Emily Vonderhaar, PhD

Clinical Research Training Fellow, Department of Microbiology & Immunology, Medical College of Wisconsin

 

Jonathan D. Van Wickle

Resident, Radiation Oncology, University of Iowa

 

Eric A. Luedke, MD

General Surgery, Sharp Memorial Hospital, Stanford Health Care-Stanford Hospital, San Diego, CA.

 

Yana Thaker, MD

General Internal Medicine, Gastroenterology, University of Washington, Seattle, WA

 

Joanne P Boisvert (Hayes), MD

Family Medicine Practice, Madras, OR

 

Egal I. Gorse, MD

2018- Fellowship Hematology and Medical Oncology, Emory University School of Medicine 2020 Recipient Nell W. and William Simpson Elkin Fellowship

 

Kimberle A Agle. PhD

Scientist-II, Immucor, Inc, Waukesha, WI

 

Amanda N. Cooper, MD

Private Practice, Dermatology, Germantown, WI

 

Luke J. Drury, PhD

Human Molecular Geneticist, Prevention Genetics, Marshfield Clinic, Marshfield, WI

 

Sheena L. Faherty

Science Writer, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), Bethesda, MD

 

Soonyean Hwang, PhD

Postdoctoral Fellow, Dana-Farber Cancer Institute, Harvard Cancer Center, Mentor: Martin E. Hemler, PhD

 

Priscilla A. Johanesen, PhD

Associate Professor (Tenured), Deputy Head of Department (Education), Department of Microbiology, Monash University, Melbourne, AUSTRALIA

 

Jennifer M. Boardman (Smith), PhD

Assistant Dean for Academic Affairs for the School of Graduate Studies, Associate Professor, Microbiology and Immunology, Department of Basic Sciences, Geisinger

 

Rebecca A. Vongsa, PhD

Scientist-III, Kimberly-Clark Corp., Skin Health and Infection Control Health Care Division, Appleton, WI

 

Michael K. Wendt, PhD

Associate Professor, Purdue University, Lafayette, IN

 

Noah P. Zimmerman, PhD

Research Manager, Arm and Hammer, Waukesha, WI

 

Mahmoud Abu Eid, PhD
Consultant, McKinsey & Company

MCW_Icons-Donate_Green

Support the Bobbie Nick Voss Laboratory at MCW

Support our research on colon and other related cancers. Please specify "Bobbie Nick Voss Lab" in the comment section on the Make a Gift page.
MCW_Icons-Donate_Green

Support the We Care Fund

This fund supports researchers and physicians who are creating cutting-edge therapies and clinical programs that benefit patients in Wisconsin and throughout the world.