Yiliang Chen Laboratory

Recent Publications

• Macrophage PIM1 Drives Atherosclerosis by Enhancing Foam Cell Formation Via CD36.

  (Beg MA, Luu QQ, Chen V, Wang Y, Xin G, Cui W, Silverstein RL, Chen Y.) Arterioscler Thromb Vasc Biol. 2026 Sep;46(9):e324938 PMID: 42558044 PMCID: PMC13464522 SCOPUS ID: 2-s2.0-105048558983 08/06/2026

• Na/K-ATPase Signaling in Adipocytes Promotes Atherosclerosis.

  (Goncalves BS, Wang Y, Pillai SS, Luu QQ, Triniac H, Lakhani HV, Chaudhry MA, Zheng Z, Shapiro JI, Silverstein RL, Sodhi K, Chen Y.) Arterioscler Thromb Vasc Biol. 2026 Aug 27 PMID: 42657466 PMCID: PMC13523103 SCOPUS ID: 2-s2.0-105048641173 08/27/2026

• Molecular mechanisms of protein disulfide isomerase antagonism by punicalagin.

  (Owegie OC, Xu RG, Kennedy QP, Penubothu T, Hancco Zirena I, Levy O, Luu QQ, Chen Y, Davizon-Castillo P, Chen Y, Yang M.) Biochem Biophys Res Commun. 2026 Aug 19;834:154462 PMID: 42623842 SCOPUS ID: 2-s2.0-105047971138 08/20/2026

• Cardiac macrophages at the crossroads of inflammation, memory, and repair.

  (Chen Y.) Immunohorizons. 2026 Feb 17;10(SI) PMID: 41758614 PMCID: PMC12947786 SCOPUS ID: 2-s2.0-105031704238 02/27/2026

• Oxidized LDL stimulates PKM2-mediated mtROS production and phagocytosis.

  (Zhang J, Chang J, Chen V, Beg MA, Huang W, Vick L, Wang Y, Zhang H, Yttre E, Gupta A, Castleberry M, Zhang Z, Dai W, Zhu J, Song S, Yang M, Brown AK, Xu Z, Ma YQ, Smith BC, Zielonka J, Traylor JG Jr, Ben Dhaou C, Orr AW, Cui W, Chen Y.) J Lipid Res. 2025 May;66(5):100809 PMID: 40250804 PMCID: PMC12142535 SCOPUS ID: 2-s2.0-105006766220 04/19/2025

• Targeting mitochondrial dynamics and redox regulation in cardiovascular diseases.

  (Beg MA, Huang M, Vick L, Rao KNS, Zhang J, Chen Y.) Trends Pharmacol Sci. 2024 Apr;45(4):290-303 PMID: 38458847 PMCID: PMC11837222 SCOPUS ID: 2-s2.0-85187360123 03/09/2024

• CD36 restricts lipid-associated macrophages accumulation in white adipose tissues during atherogenesis.

  (Chen V, Zhang J, Chang J, Beg MA, Vick L, Wang D, Gupta A, Wang Y, Zhang Z, Dai W, Kim M, Song S, Pereira D, Zheng Z, Sodhi K, Shapiro JI, Silverstein RL, Malarkannan S, Chen Y.) Front Cardiovasc Med. 2024;11:1436865 PMID: 39156133 PMCID: PMC11327822 SCOPUS ID: 2-s2.0-85201434395 08/19/2024

• Na/K-ATPase signaling tonically inhibits sodium reabsorption in the renal proximal tubule.

  (Mukherji ST, Brambilla L, Stuart KB, Mayes I, Kutz LC, Chen Y, Barbosa LA, Elmadbouh I, McDermott JP, Haller ST, Romero MF, Soleimani M, Liu J, Shapiro JI, Blanco GV, Xie Z, Pierre SV.) FASEB J. 2023 Apr;37(4):e22835 PMID: 36856735 PMCID: PMC10028530 SCOPUS ID: 2-s2.0-85149427345 03/02/2023

• Plasma tissue-type plasminogen activator is associated with lipoprotein(a) and clinical outcomes in hospitalized patients with COVID-19

  (Zhang Z, Dai W, Zhu W, Rodriguez M, Lund H, Xia Y, Chen Y, Rau M, Schneider EA, Graham MB, Jobe S, Wang D, Cui W, Wen R, Whiteheart SW, Wood JP, Silverstein R, Berger JS, Kreuziger LB, Barrett TJ, Zheng Z.) Research and Practice in Thrombosis and Haemostasis. August 2023;7(6) SCOPUS ID: 2-s2.0-85169507694 08/01/2023

• Contribution of adipocyte Na/K-ATPase α1/CD36 signaling induced exosome secretion in response to oxidized LDL.

  (Pillai SS, Pereira DG, Zhang J, Huang W, Beg MA, Knaack DA, de Souza Goncalves B, Sahoo D, Silverstein RL, Shapiro JI, Sodhi K, Chen Y.) Front Cardiovasc Med. 2023;10:1046495 PMID: 37180782 PMCID: PMC10174328 SCOPUS ID: 2-s2.0-85159873988 05/14/2023

• Na/K-ATPase suppresses LPS-induced pro-inflammatory signaling through Lyn.

  (Zhang J, Chang J, Beg MA, Huang W, Zhao Y, Dai W, Wu X, Cui W, Pillai SS, Lakhani HV, Sodhi K, Shapiro JI, Sahoo D, Zheng Z, Silverstein RL, Chen Y.) iScience. 2022 Sep 16;25(9):104963 PMID: 36072548 PMCID: PMC9442361 SCOPUS ID: 2-s2.0-85137074779 09/09/2022

• Editorial: The Roles of Lipids in Immunometabolism: The Crosstalk Between Lipid Metabolisms and Inflammation.

  (Zhang J, Dai W, Chen Y.) Front Cardiovasc Med. 2022;9:938535 PMID: 35811702 PMCID: PMC9257247 07/12/2022