Yiliang Chen Laboratory
Location
Versiti Blood Research Institute
Room 235
General Interests
Metabolism, Immunology
View Yiliang Chen, PhD Bio
Research Areas
Project 1: Study of CD36 and its signaling partners such as Na/K-ATPase in signal transduction for macrophage activation
Project 2: Study of fatty acid trafficking and regulation that is coupled with mitochondria functions
Project 3: Study of mitochondrial ROS production and their influence in efferocytosis
Project 4: Study of CD36/Pim1 pathway in foam cell formation and development of atherosclerosis
Current Members
Jackie Chang
Assistant Lab Technician
Vaya Chen, BE
Lab Technician
Lance Vick
Graduate Student
Yaxin Wang, MD
Postdoctoral Researcher
Jue Zhang, PhD
Postdoctoral Researcher
Recent Publications
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(Wolfe JT, Chen V, Chen Y, Tefft BJ.) J Thorac Cardiovasc Surg. 2025 Jul;170(1):e27-e43 PMID: 38972570 PMCID: PMC11700231 SCOPUS ID: 2-s2.0-85200217289 07/08/2024
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Role of Na/K-ATPase α1 caveolin-binding motif in adipogenesis.
(Huang M, Wang X, Chen Y, Pessoa MT, Terrell KC, Zhang J, Tian J, Xie Z, Pierre SV, Cai L.) Am J Physiol Cell Physiol. 2024 Jul 01;327(1):C48-C64 PMID: 38708522 PMCID: PMC11371328 SCOPUS ID: 2-s2.0-85196920218 05/06/2024
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Targeting mitochondrial dynamics and redox regulation in cardiovascular diseases.
(Beg MA, Huang M, Vick L, Rao KNS, Zhang J, Chen Y.) Trends Pharmacol Sci. 2024 Apr;45(4):290-303 PMID: 38458847 PMCID: PMC11837222 SCOPUS ID: 2-s2.0-85187360123 03/09/2024
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(Hou Y, Tan E, Shi H, Ren X, Wan X, Wu W, Chen Y, Niu H, Zhu G, Li J, Li Y, Wang L.) Cell Mol Life Sci. 2024 Jan 11;81(1):23 PMID: 38200266 PMCID: PMC10781825 SCOPUS ID: 2-s2.0-85181875396 01/11/2024
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(Chen V, Zhang J, Chang J, Beg MA, Vick L, Wang D, Gupta A, Wang Y, Zhang Z, Dai W, Kim M, Song S, Pereira D, Zheng Z, Sodhi K, Shapiro JI, Silverstein RL, Malarkannan S, Chen Y.) Front Cardiovasc Med. 2024;11:1436865 PMID: 39156133 PMCID: PMC11327822 SCOPUS ID: 2-s2.0-85201434395 08/19/2024
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Clinical Implications of COVID-19-Related Endothelial Dysfunction
(Aljadah M, Khan N, Beyer AM, Chen Y, Blanker A, Widlansky ME.) Jacc Advances. August 2024;3(8) SCOPUS ID: 2-s2.0-85197318304 08/01/2024
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Na/K-ATPase signaling tonically inhibits sodium reabsorption in the renal proximal tubule.
(Mukherji ST, Brambilla L, Stuart KB, Mayes I, Kutz LC, Chen Y, Barbosa LA, Elmadbouh I, McDermott JP, Haller ST, Romero MF, Soleimani M, Liu J, Shapiro JI, Blanco GV, Xie Z, Pierre SV.) FASEB J. 2023 Apr;37(4):e22835 PMID: 36856735 PMCID: PMC10028530 SCOPUS ID: 2-s2.0-85149427345 03/02/2023
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(Zhang Z, Dai W, Zhu W, Rodriguez M, Lund H, Xia Y, Chen Y, Rau M, Schneider EA, Graham MB, Jobe S, Wang D, Cui W, Wen R, Whiteheart SW, Wood JP, Silverstein R, Berger JS, Kreuziger LB, Barrett TJ, Zheng Z.) Research and Practice in Thrombosis and Haemostasis. August 2023;7(6) SCOPUS ID: 2-s2.0-85169507694 08/01/2023
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(Pillai SS, Pereira DG, Zhang J, Huang W, Beg MA, Knaack DA, de Souza Goncalves B, Sahoo D, Silverstein RL, Shapiro JI, Sodhi K, Chen Y.) Front Cardiovasc Med. 2023;10:1046495 PMID: 37180782 PMCID: PMC10174328 SCOPUS ID: 2-s2.0-85159873988 05/14/2023
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Na/K-ATPase suppresses LPS-induced pro-inflammatory signaling through Lyn.
(Zhang J, Chang J, Beg MA, Huang W, Zhao Y, Dai W, Wu X, Cui W, Pillai SS, Lakhani HV, Sodhi K, Shapiro JI, Sahoo D, Zheng Z, Silverstein RL, Chen Y.) iScience. 2022 Sep 16;25(9):104963 PMID: 36072548 PMCID: PMC9442361 SCOPUS ID: 2-s2.0-85137074779 09/09/2022
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(Chen Y, Zhang J, Cui W, Silverstein RL.) J Exp Med. 2022 Jun 06;219(6) PMID: 35438721 PMCID: PMC9022290 SCOPUS ID: 2-s2.0-85128794972 04/20/2022
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(Zhang J, Dai W, Chen Y.) Front Cardiovasc Med. 2022;9:938535 PMID: 35811702 PMCID: PMC9257247 07/12/2022