Recent Publications from the Zablocki VA Medical Center Research Laboratories

Temporal corridors of forces and moments, and injuries to pelvis-lumbar spine in vertical impact simulating underbody blast.

(Yoganandan N, Humm J, Baisden J, Moore J, Pintar F, Wassick M, Barnes D, Loftis K.) J Biomech. 2023 Mar;150:111490 PMID: 36878113 SCOPUS ID: 2-s2.0-85149387118 03/07/2023

Surface wave analysis of the skin for penetrating and non-penetrating projectile impact in porcine legs.

(LeSueur J, Hampton C, Koser J, Chirvi S, Pintar FA.) Forensic Sci Med Pathol. 2023 Mar;19(1):34-43 PMID: 36100841 09/14/2022

Response of Thoraco-Abdominal Tissue in High-Rate Compression.

(Seifert J, Koser J, Shah AS, Frazer LL, Yoganandan N, Shender BS, Sheehy JB, Paskoff G, Bentley T, Nicolella DP, Stemper BD.) J Biomech Eng. 2023 Mar 01;145(3) PMID: 36301262 SCOPUS ID: 2-s2.0-85143552239 10/28/2022

A longitudinal microstructural MRI dataset in healthy C57Bl/6 mice at 9.4 Tesla.

(Rahman N, Xu K, Budde MD, Brown A, Baron CA.) Sci Data. 2023 Feb 14;10(1):94 PMID: 36788251 PMCID: PMC9929084 SCOPUS ID: 2-s2.0-85148086939 02/15/2023

Chronicity of repeated blast traumatic brain injury associated increase in oxycodone seeking in rats.

(Chiariello R, McCarthy C, Glaeser BL, Shah AS, Budde MD, Stemper BD, Olsen CM.) Behav Brain Res. 2023 Feb 13;438:114181 PMID: 36330906 PMCID: PMC9993345 SCOPUS ID: 2-s2.0-85140915448 11/05/2022

Comparison and optimization of pCASL and VSASL for rat thoracolumbar spinal cord MRI at 9.4 T.

(Lee S, Meyer BP, Hernandez-Garcia L, Kurpad SN, Schmit BD, Budde MD.) Magn Reson Med. 2023 Feb 06 PMID: 36744728 SCOPUS ID: 2-s2.0-85147533572 02/07/2023

Correction: The Human Lumbar Spine During High-Rate Under Seat Loading: A Combined Metric Injury Criterion.

(Ortiz-Paparoni M, Op't Eynde J, Kait J, Bigler B, Shridharani J, Schmidt A, Cox C, Morino C, Pintar F, Yoganandan N, Moore J, Zhang J, Bass CR.) Ann Biomed Eng. 2023 Feb;51(2):458 PMID: 36562848 SCOPUS ID: 2-s2.0-85144642125 12/24/2022

Incorporation of concussion history as part of the LIfestyle for BRAin Health (LIBRA) modifiable factors risk score and associations with cognition in older former National Football League players.

(Brett BL, Aggarwal NT, Chandran A, Kerr ZY, Walton SR, DeFreese JD, Guskiewicz KM, Echemendia RJ, Meehan WP 3rd, McCrea MA, Mannix R.) Alzheimers Dement. 2023 Jan 28 PMID: 36708229 SCOPUS ID: 2-s2.0-85147353226 01/29/2023

Polygenic risk for mental disorders as predictors of posttraumatic stress disorder after mild traumatic brain injury.

(Stein MB, Jain S, Parodi L, Choi KW, Maihofer AX, Nelson LD, Mukherjee P, Sun X, He F, Okonkwo DO, Giacino JT, Korley FK, Vassar MJ, Robertson CS, McCrea MA, Temkin N, Markowitz AJ, Diaz-Arrastia R, Rosand J, Manley GT, TRACK-TBI Investigators.) Transl Psychiatry. 2023 Jan 25;13(1):24 PMID: 36693822 PMCID: PMC9873804 SCOPUS ID: 2-s2.0-85146843158 01/25/2023

Trends in the Use of Corticosteroids in the Management of Acute Spinal Cord Injury in North American Clinical Trials Networks (NACTN) Sites.

(Hejrati N, Aarabi B, Neal CJ, Ugiliweneza B, Kurpad SN, Shaffrey C, Guest J, Toups EG, Harrop JS, Fehlings MG.) J Neurotrauma. 2023 Jan 03 PMID: 36597351 01/05/2023

Sensitivity and Specificity of the ImPACT Neurocognitive Test in Collegiate Athletes and US Military Service Academy Cadets with ADHD and/or LD: Findings from the NCAA-DoD CARE Consortium

(Czerniak LL, Liebel SW, Zhou H, Garcia GGP, Lavieri MS, McCrea MA, McAllister TW, Pasquina PF, Broglio SP, Benjamin HJ, Brooks A, Buckley T, Cameron KL, Clugston JR, Duma SM, Eckner JT, Estevez C, Feigenbaum LA, Giza CC, Goldman JT, Hoy A, Jackson JC, Kaminski TW, Kelly LA, Kontos AP, Master CL, McDevitt J, Mihalik JP, Miles CM, Ortega J, Port N, Putukian M, Schmidt J, Susmarski A, Svoboda SJ.) Sports Medicine. March 2023;53(3):747-759 SCOPUS ID: 2-s2.0-85140043902 03/01/2023

Test-Retest Reliability and Efficacy of Individual Symptoms in Concussion Management.

(Caccese JB, Garcia GP, Kontos AP, Port N, Valerio K, Broglio SP, McCrea M, McAllister TW, Pasquina PF, Buckley TA, CARE Consortium Investigators.) Clin J Sport Med. 2023 Jan 01;33(1):52-60 PMID: 36599360 SCOPUS ID: 2-s2.0-85145547011 01/05/2023

Optimizing Concussion Care Seeking: A Longitudinal Analysis of Recovery

(Schmidt JD, Broglio SP, Knight K, Leeds D, Lynall RC, D’Lauro C, Register-Mihalik J, Kroshus E, McCrea M, McAllister TW, Kerr ZY, Hoy A, Kelly L, Master C, Ortega J, Port N, Campbell CD, Svoboda CSJ, Putukian M, Chrisman SPD, Langford D, McGinty G, Jackson JC, Cameron KL, James Susmarski A, DiFiori J, Goldman JT, Benjamin H, Buckley T, Kaminski T, Clugston JR, O’Donnell PG, Feigenbaum L, Eckner JT, Mihalik JP, Anderson S, Kontos A, Brooks MA, Miles C, Lintner L.) American Journal of Sports Medicine. January 2023;51(1):214-224 SCOPUS ID: 2-s2.0-85142937500 01/01/2023

Chronicity of repeated blast traumatic brain injury associated increase in oxycodone seeking in rats

(Chiariello R, McCarthy C, Glaeser BL, Shah AS, Budde MD, Stemper BD, Olsen CM.) Behavioural Brain Research. 13 February 2023;438 SCOPUS ID: 2-s2.0-85140915448 02/13/2023

Spinal Cord Stress After Anterior Cervical Diskectomy and Fusion: Results from a Patient-Specific Finite Element Model.

(Vedantam A, Purushothaman Y, Harinathan B, Scripp S, Budde MD, Yoganandan N.) Ann Biomed Eng. 2022 Dec 20 PMID: 36538274 SCOPUS ID: 2-s2.0-85144374871 12/21/2022

Relating American Football Age of First Exposure to Patient-Reported Outcomes and Medical Diagnoses Among Former National Football League Players: An NFL-LONG study.

(Lempke LB, Walton SR, Brett BL, Chandran A, DeFreese JD, Mannix R, Echemendia RJ, McCrea MA, Guskiewicz KM, Meehan WP 3rd, Kerr ZY.) Sports Med. 2022 Dec 07 PMID: 36479682 12/09/2022

IL-12p40 promotes secondary damage and functional impairment after spinal cord contusional injury.

(Rosas Almanza J, Stehlik KE, Page JJ, Xiong SH, Tabor EG, Aperi B, Patel K, Kodali R, Kurpad S, Budde MD, Tarima S, Swartz K, Kroner A.) J Neurosci Res. 2022 Dec;100(12):2213-2231 PMID: 36089917 SCOPUS ID: 2-s2.0-85137752150 09/13/2022

Acute Magnetic Resonance Imaging Predictors of Chronic Motor Function and Tissue Sparing in Rat Cervical Spinal Cord Injury.

(Lee SY, Schmit BD, Kurpad SN, Budde MD.) J Neurotrauma. 2022 Dec;39(23-24):1727-1740 PMID: 35708112 PMCID: PMC9734017 SCOPUS ID: 2-s2.0-85144094095 06/17/2022

Influence of bending pre-load on the tensile response of the lumbar spine.

(Avila J, Humm J, Driesslein K, Moorcroft D, Pintar F.) J Biomech. 2022 Dec;145:111367 PMID: 36343414 SCOPUS ID: 2-s2.0-85141250712 11/08/2022

The Evolving Profile of Acute Spinal Cord Injury Demographics, Outcomes and Surgical Treatment in North America: Analysis of a Prospective Multicenter Dataset of 989 Patients.

(Vedantam A, Ugiliweneza B, Williamson T, Guest J, Harrop JS, Tator C, Aarabi B, Fehlings MG, Kurpad SN, Neal CJ.) J Neurotrauma. 2022 Nov 30 PMID: 36448585 12/01/2022

Differential Trajectory of Diffusion and Perfusion Magnetic Resonance Imaging of Rat Spinal Cord Injury.

(Meyer BP, Lee SY, Kurpad SN, Budde MD.) J Neurotrauma. 2022 Nov 07 PMID: 36226406 10/14/2022

Consensus Head Acceleration Measurement Practices (CHAMP): Study Design and Statistical Analysis.

(Rowson S, Mihalik J, Urban J, Schmidt J, Marshall S, Harezlak J, Stemper BD, McCrea M, Funk J.) Ann Biomed Eng. 2022 Nov;50(11):1346-1355 PMID: 36253602 PMCID: PMC9652215 SCOPUS ID: 2-s2.0-85140002883 10/18/2022

Time Delta Head Impact Frequency: An Analysis on Head Impact Exposure in the Lead Up to a Concussion: Findings from the NCAA-DOD Care Consortium.

(Seifert J, Shah AS, Harezlak J, Rowson S, Mihalik JP, Riggen L, Duma S, Brooks A, Cameron KL, Giza CC, Goldman J, Guskiewicz KM, Houston MN, Jackson JC, McGinty G, Pasquina P, Broglio SP, McAllister TW, McCrea MA, Stemper BD.) Ann Biomed Eng. 2022 Nov;50(11):1473-1487 PMID: 35933459 PMCID: PMC9652163 SCOPUS ID: 2-s2.0-85135698130 08/07/2022

Calcaneus fracture pattern and severity: Role of local trabecular bone density.

(Chirvi S, Pahapill N, Yoganandan N, Curry W, Stemper B, Kleinberger M, Pintar FA.) J Mech Behav Biomed Mater. 2022 Oct;134:105332 PMID: 35987107 SCOPUS ID: 2-s2.0-85136013753 08/21/2022

Normalization technique to build patient specific muscle model in finite element head neck spine.

(Varghese V, Baisden J, Yoganandan N.) Med Eng Phys. 2022 Sep;107:103857 PMID: 36068040 SCOPUS ID: 2-s2.0-85134890990 09/07/2022

Dysregulation of Iron Homeostasis in the Central Nervous System and the Role of Ferroptosis in Neurodegenerative Disorders.

(David S, Jhelum P, Ryan F, Jeong SY, Kroner A.) Antioxid Redox Signal. 2022 Jul;37(1-3):150-170 PMID: 34569265 09/28/2021

We Choose to Call it 'Degenerative Cervical Myelopathy': Findings of AO Spine RECODE-DCM, an International and Multi-Stakeholder Partnership to Agree a Standard Unifying Term and Definition for a Disease.

(Davies BM, Khan DZ, Barzangi K, Ali A, Mowforth OD, Nouri A, Harrop JS, Aarabi B, Rahimi-Movaghar V, Kurpad SN, Guest JD, Tetreault L, Kwon BK, Boerger TF, Rodrigues-Pinto R, Furlan JC, Chen R, Zipser CM, Curt A, Milligan J, Kalsi-Rayn S, Sarewitz E, Sadler I, Widdop S, Fehlings MG, Kotter MRN.) Global Spine J. 2022 Jun 29:21925682221111780 PMID: 35769029 07/01/2022

Ferroptosis in Neurological Disease.

(David S, Ryan F, Jhelum P, Kroner A.) Neuroscientist. 2022 Jun 08:10738584221100183 PMID: 35678019 06/10/2022

Viral tools for mapping and modulating neural networks after spinal cord injury.

(Schrank S, Satkunendrarajah K.) Exp Neurol. 2022 May;351:113995 PMID: 35123955 SCOPUS ID: 2-s2.0-85124103217 02/07/2022

Comparison of small female occupant model responses with experimental data in a reclined posture.

(Umale S, Khandelwal P, Humm J, Pintar F, Yoganandan N.) Traffic Inj Prev. 2022;23(sup1):S211-S213 PMID: 36223530 SCOPUS ID: 2-s2.0-85139868411 10/13/2022

Loading rate effect on tradeoff of fractures from pelvis to lumbar spine under axial impact loading.

(Yoganandan N, Moore J, Humm J, Pintar F, Baisden J, Barnes D, Loftis K.) Traffic Inj Prev. 2022;23(sup1):S26-S31 PMID: 36095155 SCOPUS ID: 2-s2.0-85138570361 09/13/2022

Spinal cord injury and degenerative cervical myelopathy.

(Satkunendrarajah K, Karadimas SK, Fehlings MG.) Handb Clin Neurol. 2022;189:241-257 PMID: 36031307 SCOPUS ID: 2-s2.0-85136594983 08/29/2022

Morphometry of lumbar muscles in the seated posture with weight-bearing MR scans

(Varghese V, Yoganandan N, Baisden J, Choi H, Banerjee A.) Journal of Clinical Orthopaedics and Trauma. December 2022;35 SCOPUS ID: 2-s2.0-85140807080 12/01/2022

Mechanisms of cervical spine injury and coupling response with initial head rotated posture - implications for AIS coding.

(Yoganandan N, Baisden J, Humm J, Varghese V.) Traffic Inj Prev. 2022;23(sup1):S195-S198 PMID: 36215262 SCOPUS ID: 2-s2.0-85139922748 10/11/2022

Normalization technique to build patient specific muscle model in finite element head neck spine

(Varghese V, Baisden J, Yoganandan N.) Medical Engineering and Physics. September 2022;107 SCOPUS ID: 2-s2.0-85134890990 09/01/2022

Correction to: CCL3 contributes to secondary damage after spinal cord injury.

(Pelisch N, Almanza JR, Stehlik KE, Aperi BV, Kroner A.) J Neuroinflammation. 2021 Apr 03;18(1):87 PMID: 33812368 PMCID: PMC8019158 04/05/2021

Spinal Interneurons as Gatekeepers to Neuroplasticity after Injury or Disease.

(Zholudeva LV, Abraira VE, Satkunendrarajah K, McDevitt TC, Goulding MD, Magnuson DSK, Lane MA.) J Neurosci. 2021 Feb 03;41(5):845-854 PMID: 33472820 PMCID: PMC7880285 SCOPUS ID: 2-s2.0-85101994444 01/22/2021

Use of a Self-Delivering Anti-CCL3 FANA Oligonucleotide as an Innovative Approach to Target Inflammation after Spinal Cord Injury.

(Pelisch N, Rosas Almanza J, Stehlik KE, Aperi BV, Kroner A.) eNeuro. 2021;8(2) PMID: 33632814 PMCID: PMC7986543 02/27/2021

Mir21 modulates inflammation and sensorimotor deficits in cervical myelopathy: data from humans and animal models.

(Laliberte AM, Karadimas SK, Vidal PM, Satkunendrarajah K, Fehlings MG.) Brain Commun. 2021;3(1):fcaa234 PMID: 33604572 PMCID: PMC7878254 02/20/2021

CCL3 contributes to secondary damage after spinal cord injury.

(Pelisch N, Rosas Almanza J, Stehlik KE, Aperi BV, Kroner A.) J Neuroinflammation. 2020 Nov 27;17(1):362 PMID: 33246483 PMCID: PMC7694914 11/29/2020

Bilateral cervical contusion spinal cord injury: A mouse model to evaluate sensorimotor function.

(Reinhardt DR, Stehlik KE, Satkunendrarajah K, Kroner A.) Exp Neurol. 2020 Sep;331:113381 PMID: 32561411 SCOPUS ID: 2-s2.0-85086575731 06/21/2020

Sensory cortical control of movement.

(Karadimas SK, Satkunendrarajah K, Laliberte AM, Ringuette D, Weisspapir I, Li L, Gosgnach S, Fehlings MG.) Nat Neurosci. 2020 Jan;23(1):75-84 PMID: 31740813 SCOPUS ID: 2-s2.0-85075146992 11/20/2019

Prolonged functional optical sensitivity in non-human primate motor nerves following cyclosporine-based immunosuppression and rAAV2-retro mediated expression of ChR2

(Williams JJ, Vazquez AL, Schwartz AB.) International IEEE/EMBS Conference on Neural Engineering, NER. 16 May 2019;2019-March:534-537 SCOPUS ID: 2-s2.0-85066753496 05/16/2019

Viral-Mediated Optogenetic Stimulation of Peripheral Motor Nerves in Non-human Primates.

(Williams JJ, Watson AM, Vazquez AL, Schwartz AB.) Front Neurosci. 2019;13:759 PMID: 31417342 PMCID: PMC6684788 08/17/2019

Multi-scale, multi-modal analysis uncovers complex relationship at the brain tissue-implant neural interface: new emphasis on the biological interface.

(Michelson NJ, Vazquez AL, Eles JR, Salatino JW, Purcell EK, Williams JJ, Cui XT, Kozai TDY.) J Neural Eng. 2018 Jun;15(3):033001 PMID: 29182149 PMCID: PMC5967409 SCOPUS ID: 2-s2.0-85047317370 11/29/2017

Spatial co-adaptation of cortical control columns in a micro-ECoG brain-computer interface.

(Rouse AG, Williams JJ, Wheeler JJ, Moran DW.) J Neural Eng. 2016 Oct;13(5):056018 PMID: 27651034 09/22/2016

Idle state classification using spiking activity and local field potentials in a brain computer interface.

(Williams JJ, Tien RN, Inoue Y, Schwartz AB.) Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:1572-1575 PMID: 28268628 SCOPUS ID: 2-s2.0-85009083903 03/09/2017

Differentiating closed-loop cortical intention from rest: building an asynchronous electrocorticographic BCI.

(Williams JJ, Rouse AG, Thongpang S, Williams JC, Moran DW.) J Neural Eng. 2013 Aug;10(4):046001 PMID: 23715295 SCOPUS ID: 2-s2.0-84883151862 05/30/2013