Research Mentoring and Training Opportunities
There are multiple other basic investigators involved with the Cardiovascular Research Center who can provide mentorship to fellows depending on research interest.
John Baker, PhD | Professor, Surgery
Dr. Baker's research aims to gain understanding of the mechanisms by which adaptation of the heart to chronic hypoxia increases resistance to subsequent ischemia. He is also involved in determining the role of radiation in cardiovascular disease.
Michael Cinquegrani, MD | Professor and Vice Chair of Heart and Vascular Service Line
Dr. Cinquegrani's research interests include interventional cardiology, closure of patent foramen ovale, coronary imaging with CT and relationship between renal disease and cardiovascular disease.
David Gutterman, MD | Professor and Sr. Associate Director, Cardiovascular Center
Dr. Gutterman is a pioneer in studying the mechanisms of microcirculatory dysfunction and discovering novel signaling by reactive oxygen species. He is a world expert on the mechanisms underlying flow-mediated dilation of coronary microvessels and the role of signaling pathways such as hydrogen peroxide in various vascular diseases such as atherosclerosis, diabetes, and metabolic syndrome.
David Harder, PhD | Associate Dean of Research Mentoring; Professor, Physiology, Medicine and pediatrics
Dr. Harder's research involves studying cytochrome p450 metabolites and vascular tone, shear activated ion channels in vascular endothelial cells, vascular autoregulation, and membrane lipids in vascular muscle.
Jason Jurva, MD | Assistant Professor
Dr. Jurva's research interests include echocardiography and vascular endothelial function.
Jacquelyn Kulinski, MD | Assistant Professor
Dr. Kulinski’s focus is on preventive cardiology, particularly lifestyle behaviors such as diet and physical inactivity. Her research interests include determinants of cardiorespiratory fitness and sedentary behavior and physiology. Her research emphasizes the use of accelerometers to objectively measure the amount and intensity of physical activity. She is currently studying the association of exercise and ‘sitting too much’ on coronary artery calcium burden. Future research plans include evaluating the feasibility of interventions to reduce sitting time in sedentary populations, with the goal of reducing future cardiovascular risk.
John LaDisa, PhD | Adjunct Assistant Professor (Cardiovascular Medicine) Assistant Professor Biophysics
Dr. LaDisa is involved in using computational fluid dynamics simulations to understand vascular physiology in atherosclerotic disease and congenital heart failure. He is developing innovative means of optimizing stent design.
David Marks, MD | Associate Professor and Vice-Chair of Medicine
Dr. Marks heads the Clinical Trials Program of the Cardiovascular Division. His research interests include interventional cardiology, percutaneous mitral repair, coronary CT imaging, and patent foramen ovale closure.
Hiroto Miura, PhD | Adjunct Associate Professor (Cardiovascular Medicine)
Dr. Miura is involved in research on calcium-activated potassium channel KCa3.1's role in atherogenesis and studying reactive oxygen species in endothelial dysfunction.
Jason Rubenstein, MD | Assistant Professor
Dr. Rubenstein's research interests include arrhythmia prognostication and prevention, myocardial infarct scar imaging using MRI.
Jennifer Strande, MD, PhD | Assistant Professor
Dr. Strande conducts both clinical and basic research in the areas of dystrophic cardiomyopathy and heart failure with preserved ejection fraction (HFpEF).
David Warltier, MD, phD | Professor of Anesthesiology and Medicine/Cardiology
Dr. Warltier's projects include studying the pharmacology and pathophysiology of left ventricular systolic and diastolic function in the normal and failing heart (specifically interested in time course and left ventricular mechanical alterations during development of pacing-induced cardiomyopathy/ischemic cardiomyopathy/myocardial stunning), development of new therapeutic modalities for the treatment of coronary collateral circulation, development of impedance catheter hardware for instantaneous measurement of either left ventricular or right ventricular diastolic function and new pharmacological agents that can be used to prevent ischemia/infarction in the perioperative period (techniques include holter analysis of ST segment alterations before, during, and after surgery to quantify intensity of ischemia).
Michael Widlansky, MD | Associate Professor, Cardiovascular Medicine and Pharmacology
Dr. Widlansky's lab concentrates on assessing the mechanisms involved in vascular endothelial regulation in humans. His studies apply high resolution vascular ultrasound and forearm blood flow measurements to make in vivo assess the effects of mechanistic interventions on vascular endothelial function. His current studies concentrate on assessing the role of mitochondria in the endothelial dysfunction of Type II Diabetics. Dr. Widlansky also currently leads the Human Vascular Research Center at MCW and is involved in multiple collaborative studies involving the Departments of Pediatrics (Endocrinology and Cardiology) Orthopedics, Surgery, and Medicine (Endocrinology and Geriatrics). These collaborative efforts assess alterations in vascular endothelial function in relevant disease states.
Xuefeng Zhang, PhD | Adjunct Assistant Professor (Cardiovascular Medicine)
Dr. Zhang is involved in research on coronary vascular physiology including role of mitochondrial reactive oxygen species and transient receptor potential vanilloid type 4 (TRPV4) channels in endothelial dysfunction.
Ming Zhao, PhD | Adjunct Assistant Professor (Cardiovascular Medicine), Assistant Professor Biophysics
Dr. Zhao is involved in developing novel imaging compounds to non-invasively detect cell death in myocardial infarction, transplant rejection, cardiomyopathy.